ID 2.1.1.299 DE protein N-terminal monomethyltransferase. AN N-terminal monomethylase. CA (1) N-terminal L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L- CA methionine = H(+) + N-terminal N-methyl-L-alanyl-L-prolyl-L-lysyl- CA [protein] + S-adenosyl-L-homocysteine. CA (2) N-terminal L-prolyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L- CA methionine = H(+) + N-terminal N-methyl-L-prolyl-L-prolyl-L-lysyl- CA [protein] + S-adenosyl-L-homocysteine. CA (3) N-terminal L-seryl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L- CA methionine = H(+) + N-terminal N-methyl-L-seryl-L-prolyl-L-lysyl- CA [protein] + S-adenosyl-L-homocysteine. CC -!- This enzyme methylates the N-terminus of target proteins containing CC the N-terminal motif [Ala/Pro/Ser]-Pro-Lys after the initiator CC L-methionine is cleaved. CC -!- In contrast to EC 2.1.1.244, the protein only adds one methyl group CC to the N-terminal. DR B8JM82, NTM1B_DANRE; Q5VVY1, NTM1B_HUMAN; B2RXM4, NTM1B_MOUSE; DR D3ZVR1, NTM1B_RAT ; //