ENZYME entry: EC 2.1.1.304

Accepted Name
L-tyrosine C(3)-methyltransferase.
Reaction catalysed
S-adenosyl-L-methionine + L-tyrosine <=> S-adenosyl-L-homocysteine + 3-methyl-L-tyrosine
Comment(s)
The enzyme from the bacterium Streptomyces lavendulae is involved in biosynthesis of saframycin A, a potent antitumor antibiotic that belongs to the tetrahydroisoquinoline family.
Cross-references
BRENDA2.1.1.304
EC2PDB2.1.1.304
ExplorEnz2.1.1.304
PRIAM enzyme-specific profiles2.1.1.304
KEGG Ligand Database for Enzyme Nomenclature2.1.1.304
IUBMB Enzyme Nomenclature2.1.1.304
IntEnz2.1.1.304
MEDLINEFind literature relating to 2.1.1.304
MetaCyc2.1.1.304
UniProtKB/Swiss-Prot
B0CN31, SFMM2_STRLA

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