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ENZYME entry: EC 2.1.1.37

Accepted Name
DNA (cytosine-5-)-methyltransferase.
Alternative Name(s)
Cytosine 5-methyltransferase.
Cytosine DNA methylase.
Cytosine DNA methyltransferase.
Cytosine-specific DNA methyltransferase.
Deoxyribonucleate methylase.
Deoxyribonucleate methyltransferase.
Deoxyribonucleic (cytosine-5-)-methyltransferase.
Deoxyribonucleic acid (cytosine-5-)-methyltransferase.
Deoxyribonucleic acid methylase.
Deoxyribonucleic acid methyltransferase.
Deoxyribonucleic acid modification methylase.
Deoxyribonucleic methylase.
DNA 5-cytosine methylase.
DNA cytosine C(5) methylase.
DNA cytosine methylase.
DNA methylase.
DNA methyltransferase.
DNA transmethylase.
DNA-cytosine 5-methylase.
DNA-cytosine methyltransferase.
Methylphosphotriester-DNA methyltransferase.
Modification methylase.
Restriction-modification system.
Site-specific DNA-methyltransferase (cytosine-specific).
Type II DNA methylase.
Reaction catalysed
S-adenosyl-L-methionine + DNA <=> S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine
Comment(s)
  • See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/
  • Formerly EC 2.1.1.73.
Cross-references
PROSITEPDOC00089
BRENDA2.1.1.37
EC2PDB2.1.1.37
ExplorEnz2.1.1.37
PRIAM enzyme-specific profiles2.1.1.37
KEGG Ligand Database for Enzyme Nomenclature2.1.1.37
IUBMB Enzyme Nomenclature2.1.1.37
IntEnz2.1.1.37
MEDLINEFind literature relating to 2.1.1.37
MetaCyc2.1.1.37
UniProtKB/Swiss-Prot
O49139, CMT1_ARATH;  Q54JH6, CMT1_DICDI;  Q9AXT8, CMT1_MAIZE;  
A0A0P0VUY4, CMT1_ORYSJ;  Q94F87, CMT2_ARATH;  Q9ARI6, CMT2_MAIZE;  
Q5KQL9, CMT2_ORYSJ;  Q94F88, CMT3_ARATH;  Q8LPU5, CMT3_MAIZE;  
C0SQ89, CMT3_ORYSJ;  P0AEE0, DCM_ECO57;  P0AED9, DCM_ECOLI;  
Q7Y1I7, DNM1A_ORYSJ;  B1Q3J6, DNM1B_ORYSJ;  Q4W5Z4, DNM3A_CHICK;  
Q9Y6K1, DNM3A_HUMAN;  O88508, DNM3A_MOUSE;  Q1LZ53, DNM3A_RAT;  
Q9UBC3, DNM3B_HUMAN;  O88509, DNM3B_MOUSE;  P0DOY1, DNM3C_MOUSE;  
P34881, DNMT1_ARATH;  Q24K09, DNMT1_BOVIN;  Q92072, DNMT1_CHICK;  
P26358, DNMT1_HUMAN;  P13864, DNMT1_MOUSE;  Q27746, DNMT1_PARLI;  
Q9Z330, DNMT1_RAT;  Q9M0S8, DNMT2_ARATH;  Q9T0I1, DNMT3_ARATH;  
O23273, DNMT4_ARATH;  Q67472, DNMT_FRG3G;  Q2RBJ4, DRM1A_ORYSJ;  
Q9LXE5, DRM1L_ARATH;  Q9M548, DRM2_ARATH;  Q10SU5, DRM2_ORYSJ;  
Q8EL95, MT36_OCEIH;  Q57983, MT51_METJA;  Q58600, MT52_METJA;  
O52702, MTA1_ACEPA;  P31974, MTA1_CELCE;  P94147, MTA1_THAGE;  
P34882, MTAA_SYNP2;  P34883, MTAB_SYNP2;  D4ZX35, MTAP_ARTPN;  
P34905, MTB1_BREBE;  P10283, MTB1_BREEP;  P25262, MTB1_HERAU;  
P13906, MTB1_LYSSH;  Q59603, MTB1_NEIGO;  Q59605, MTB5_NEIGO;  
P43420, MTB6_BACSF;  P19888, MTBA_ANEAE;  P09389, MTBB_BPSPB;  
P17044, MTBF_BACIU;  P68585, MTBP_BACSU;  P68586, MTBP_BPPHT;  
P06530, MTBR_BACIU;  P09915, MTBR_BPRH1;  P00476, MTBS_BPSPR;  
P25263, MTC1_HERAU;  P36216, MTC1_PBCVI;  P25264, MTC2_HERAU;  
P05302, MTD1_DESNO;  P24600, MTD1_HERAU;  Q9RLM4, MTD1_NEIMC;  
P25265, MTD2_HERAU;  P50185, MTD5_DACSA;  P25266, MTE1_HERAU;  
P05101, MTE2_ECOLX;  P50196, MTE8_ECOLX;  P34906, MTF1_FUSNU;  
Q59606, MTF7_NEIGO;  P25282, MTG1_AVIPA;  P25267, MTG1_HERAU;  
P25283, MTG2_AVIPA;  P05102, MTH1_HAEPH;  O30868, MTH2_HAEAE;  
P15446, MTH2_HAEPA;  P20589, MTH3_HAEAE;  P45000, MTH5_HAEIN;  
P50192, MTHA_HAEPH;  P29567, MTHT_METTF;  P11408, MTM1_MORSP;  
P31033, MTM4_NEIGO;  P50188, MTN1_NOCAE;  P50182, MTN4_NEILA;  
P24581, MTNX_NEILA;  O33481, MTP1_PSYTA;  P08455, MTP2_NEIGO;  
P09795, MTS1_SALIN;  O31073, MTS1_STRAH;  P34879, MTS2_SHISO;  
P16668, MTS3_STAAU;  P23737, MTS9_STAAU;  P34877, MTSA_LACLC;  
P34878, MTSB_LACLC;  P15840, MTSI_SPISQ;  P52311, MTX2_XANOR;  
O34939, YDIO_BACSU;  O34680, YDIP_BACSU;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.1.-
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