ID   2.1.1.379
DE   [methyl coenzyme M reductase]-L-arginine C-5-methyltransferase.
AN   methanogenesis marker protein 10.
CA   AH2 + L-arginyl-[methyl-coenzyme M reductase] + 2 S-adenosyl-L-methionine
CA   = (5S)-C-methyl-L-arginyl-[methyl-coenzyme M reductase] +
CA   5'-deoxyadenosine + A + 2 H(+) + L-methionine + S-adenosyl-L-
CA   homocysteine.
CC   -!- The enzyme, present in methanogenic archaea, catalyzes a modification
CC       of an L-arginine residue at the active site of EC 2.8.4.1, which
CC       catalyzes the last and methane-releasing step of methanogenesis.
CC   -!- The enzyme is a radical AdoMet (radical SAM) enzyme and contains an
CC       [4Fe-4S] cluster and a Coalpha-[alpha-(5-hydroxybenzimidazolyl)]-
CC       cobamide cofactor.
CC   -!- The methyl group, which is derived from S-adenosyl-L-methionine,
CC       is transferred to the cob(I)amide cofactor, forming
CC       methylcob(III)amide as an intermediate carrier, before being
CC       transferred to the arginine residue.
DR   Q8THG6, MCRAM_METAC;  Q58251, MCRAM_METJA;
//