ENZYME entry: EC 2.1.1.4

Accepted Name
Acetylserotonin O-methyltransferase.
Alternative Name(s)
Hydroxyindole O-methyltransferase.
Reaction catalysed
S-adenosyl-L-methionine + N-acetylserotonin <=> S-adenosyl-L-homocysteine + melatonin
Comment(s)
Some other hydroxyindoles also act as acceptor, more slowly.
Cross-references
BRENDA2.1.1.4
EC2PDB2.1.1.4
ExplorEnz2.1.1.4
PRIAM enzyme-specific profiles2.1.1.4
KEGG Ligand Database for Enzyme Nomenclature2.1.1.4
IUBMB Enzyme Nomenclature2.1.1.4
IntEnz2.1.1.4
MEDLINEFind literature relating to 2.1.1.4
MetaCyc2.1.1.4
UniProtKB/Swiss-Prot
P10950, ASMT_BOVIN;  Q92056, ASMT_CHICK;  P46597, ASMT_HUMAN;  
Q8HZJ0, ASMT_MACMU;  D3KU66, ASMT_MOUSE;  D3KU67, ASMT_MUSMM;  
B3GSH5, ASMT_RAT;  

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