ID 2.1.1.41 DE sterol 24-C-methyltransferase. AN 24-sterol C-methyltransferase. AN Delta(24)-methyltransferase. AN Delta(24)-sterol methyltransferase. AN phytosterol methyltransferase. AN S-adenosyl-4-methionine:sterol Delta(24)-methyltransferase. AN S-adenosyl-L-methionine:Delta(24(23))-sterol methyltransferase. AN SMT1. AN zymosterol-24-methyltransferase. CA S-adenosyl-L-methionine + zymosterol = fecosterol + H(+) + S-adenosyl-L- CA homocysteine. CC -!- Acts on a range of sterols with a 24(25)-double bond in the side CC chain. CC -!- While zymosterol is the preferred substrate it also acts on CC desmosterol, 5alpha-cholesta-7,24-dien-3beta-ol, 5alpha-cholesta- CC 5,7,24-trien-3beta-ol, 4alpha-methylzymosterol and others. CC -!- S-Adenosyl-L-methionine attacks the Si face of the 24(25) double bond CC and the C-24 hydrogen is transferred to C-25 on the Re face of the CC double bond. DR O74198, ERG6_CANAL ; Q6FRZ7, ERG6_CANGA ; Q875K1, ERG6_CLAL4 ; DR Q6BRB7, ERG6_DEBHA ; Q759S7, ERG6_EREGS ; Q6CYB3, ERG6_KLULA ; DR L7IP31, ERG6_PYRO3 ; P0CT10, ERG6_PYRO7 ; O14321, ERG6_SCHPO ; DR Q6C2D9, ERG6_YARLI ; P25087, ERG6_YEAST ; Q9LM02, SMT1_ARATH ; DR Q54I98, SMT1_DICDI ; Q6ZIX2, SMT1_ORYSJ ; //