ID   2.1.1.49
DE   amine N-methyltransferase.
AN   arylamine N-methyltransferase.
AN   nicotine N-methyltransferase.
AN   tryptamine N-methyltransferase.
CA   (1) a primary amine + S-adenosyl-L-methionine = a methylated primary
CA   amine + H(+) + S-adenosyl-L-homocysteine.
CA   (2) a secondary amine + S-adenosyl-L-methionine = a methylated secondary
CA   amine + H(+) + S-adenosyl-L-homocysteine.
CA   (3) a tertiary amine + S-adenosyl-L-methionine = a methylated tertiary
CA   amine + H(+) + S-adenosyl-L-homocysteine.
CC   -!- An enzyme of very broad specificity; many primary, secondary and
CC       tertiary amines can act as acceptors, including tryptamine, aniline,
CC       nicotine and a variety of drugs and other xenobiotics.
CC   -!- Formerly EC 2.1.1.81.
DR   O95050, INMT_HUMAN ;  P40936, INMT_MOUSE ;  Q5RFR7, INMT_PONAB ;
DR   O97972, INMT_RABIT ;
//