ENZYME entry: EC 2.1.1.6

Accepted Name
Catechol O-methyltransferase.
Reaction catalysed
S-adenosyl-L-methionine + a catechol <=> S-adenosyl-L-homocysteine + a guaiacol
Comment(s)
The mammalian enzymes act more rapidly on catecholamines such as adrenaline or noradrenaline than on catechols.
Cross-references
BRENDA2.1.1.6
EC2PDB2.1.1.6
ExplorEnz2.1.1.6
PRIAM enzyme-specific profiles2.1.1.6
KEGG Ligand Database for Enzyme Nomenclature2.1.1.6
IUBMB Enzyme Nomenclature2.1.1.6
IntEnz2.1.1.6
MEDLINEFind literature relating to 2.1.1.6
MetaCyc2.1.1.6
UniProtKB/Swiss-Prot
O42898, COMT1_SCHPO;  Q8NKC1, COMT2_SCHPO;  A7MBI7, COMT_BOVIN;  
Q5H879, COMT_HORSE;  P21964, COMT_HUMAN;  O88587, COMT_MOUSE;  
Q99028, COMT_PIG;  P22734, COMT_RAT;  Q8WZ04, TOMT_HUMAN;  
B6CZ46, TOMT_MACMU;  A1Y9I9, TOMT_MOUSE;  P86243, TOMT_PANTR;  
B6CZ56, TOMT_PROCO;  B6CZ62, TOMT_RAT;  

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