ENZYME entry: EC 2.1.1.6
| Accepted Name |
|---|
| Catechol O-methyltransferase.
|
| Reaction catalysed |
|---|
| S-adenosyl-L-methionine + a catechol <=> S-adenosyl-L-homocysteine + a guaiacol |
| Comment(s) |
|---|
| The mammalian enzymes act more rapidly on catecholamines such as
adrenaline or noradrenaline than on catechols.
|
| Cross-references |
|---|
| BRENDA | 2.1.1.6 |
| EC2PDB | 2.1.1.6 |
| ExplorEnz | 2.1.1.6 |
| PRIAM enzyme-specific profiles | 2.1.1.6 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.1.1.6 |
| IUBMB Enzyme Nomenclature | 2.1.1.6 |
| IntEnz | 2.1.1.6 |
| MEDLINE | Find literature relating to 2.1.1.6 |
| MetaCyc | 2.1.1.6 |
| UniProtKB/Swiss-Prot |
| O42898, COMT1_SCHPO; | Q8NKC1, COMT2_SCHPO; | A7MBI7, COMT_BOVIN; |
| Q5H879, COMT_HORSE; | P21964, COMT_HUMAN; | O88587, COMT_MOUSE; |
| Q99028, COMT_PIG; | P22734, COMT_RAT; | Q8WZ04, TOMT_HUMAN; |
| B6CZ46, TOMT_MACMU; | A1Y9I9, TOMT_MOUSE; | P86243, TOMT_PANTR; |
| B6CZ56, TOMT_PROCO; | B6CZ62, TOMT_RAT; |
|
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