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ENZYME entry: EC 2.1.1.n8
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|Small RNA 2'-O-methyltransferase.
|S-adenosyl-L-methionine + small RNA <=> S-adenosyl-L-homocysteine + small RNA containing a 3'-terminal 2'-O-methylnucleotide|
- Adds a methyl group to the ribose of the last nucleotide of small
- This protects the 3'-end of sRNAs from uridylation activity and
- Can methylates 3'-end of microRNAs (miRNAs), small interfering RNAs
(siRNas) and trans-acting small interfering RNAs (ta-siRNAs).
|Q9C5Q8, HEN1_ARATH; ||H9JDT2, HENMT_BOMMO; ||E1BVR9, HENMT_CHICK; |
|Q568P9, HENMT_DANRE; ||Q7K175, HENMT_DROME; ||Q5T8I9, HENMT_HUMAN; |
|Q4R3W5, HENMT_MACFA; ||Q8CAE2, HENMT_MOUSE; ||Q32PY6, HENMT_RAT; |
|Q9UST9, HENMT_SCHPO; ||Q230X8, HENMT_TETTS; ||C0IN03, HENMT_XENTR; |
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entries corresponding to 2.1.1.-
entries corresponding to 2.1.-.-
entries corresponding to 2.-.-.-