ENZYME entry: EC 2.1.2.3

Accepted Name
Phosphoribosylaminoimidazolecarboxamide formyltransferase.
Alternative Name(s)
10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4- imidazolecarboxamide formyltransferase.
5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase.
5-amino-1-ribosyl-4-imidazolecarboxamide 5'-phosphate transformylase.
5-amino-4-imidazolecarboxamide ribonucleotide transformylase.
5-amino-4-imidazolecarboxamide ribotide transformylase.
AICAR formyltransferase.
AICAR transformylase.
Aminoimidazolecarboxamide ribonucleotide transformylase.
Reaction catalysed
10-formyltetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide <=> tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide
Cross-references
BRENDA2.1.2.3
EC2PDB2.1.2.3
ExplorEnz2.1.2.3
PRIAM enzyme-specific profiles2.1.2.3
KEGG Ligand Database for Enzyme Nomenclature2.1.2.3
IUBMB Enzyme Nomenclature2.1.2.3
IntEnz2.1.2.3
MEDLINEFind literature relating to 2.1.2.3
MetaCyc2.1.2.3
UniProtKB/Swiss-Prot
P54113, PUR91_YEAST;  P38009, PUR92_YEAST;  B0BZH9, PUR9_ACAM1;  
A5FUH4, PUR9_ACICJ;  B7J5P7, PUR9_ACIF2;  B5EL42, PUR9_ACIF5;  
A0KGJ2, PUR9_AERHH;  A4SR98, PUR9_AERS4;  B9JEU9, PUR9_AGRRK;  
Q8UBM8, PUR9_AGRT5;  Q0VMY5, PUR9_ALCBS;  B6ENA8, PUR9_ALISL;  
A6TLS7, PUR9_ALKMQ;  A8MLI9, PUR9_ALKOO;  Q46480, PUR9_ALLVD;  
B4S133, PUR9_ALTMD;  B8JHC9, PUR9_ANAD2;  Q2IKQ7, PUR9_ANADE;  
A7HA60, PUR9_ANADF;  B4UJ61, PUR9_ANASK;  Q3M6G3, PUR9_ANAVT;  
B7GFU2, PUR9_ANOFW;  O67775, PUR9_AQUAE;  C1DLJ1, PUR9_AZOVD;  
C3PBN4, PUR9_BACAA;  C3L536, PUR9_BACAC;  A0R900, PUR9_BACAH;  
Q81ZG8, PUR9_BACAN;  B7JM89, PUR9_BACC0;  Q73EN1, PUR9_BACC1;  
B7IUV7, PUR9_BACC2;  C1EV67, PUR9_BACC3;  B7H4U0, PUR9_BACC4;  
B7HS36, PUR9_BACC7;  A7GKI2, PUR9_BACCN;  B9J1K9, PUR9_BACCQ;  
Q81IP9, PUR9_BACCR;  Q63GS9, PUR9_BACCZ;  Q9KF53, PUR9_BACHD;  
Q6HPA0, PUR9_BACHK;  Q5WJ82, PUR9_BACSK;  P12048, PUR9_BACSU;  
Q8A155, PUR9_BACTN;  A9VRF5, PUR9_BACWK;  A1UR09, PUR9_BARBK;  
Q6G5S5, PUR9_BARHE;  Q6FYG4, PUR9_BARQU;  A9IZD0, PUR9_BART1;  
Q1LU51, PUR9_BAUCH;  B3DRY6, PUR9_BIFLD;  Q8G6B1, PUR9_BIFLO;  
Q0VCK0, PUR9_BOVIN;  Q89WU7, PUR9_BRADU;  C0QXU6, PUR9_BRAHW;  
B2S7P0, PUR9_BRUA1;  Q2YLH0, PUR9_BRUA2;  Q57B71, PUR9_BRUAB;  
A9M854, PUR9_BRUC2;  C0RF67, PUR9_BRUMB;  P67539, PUR9_BRUME;  
A5VSF8, PUR9_BRUO2;  A9WWU1, PUR9_BRUSI;  P67540, PUR9_BRUSU;  
B8D8J3, PUR9_BUCA5;  P57143, PUR9_BUCAI;  Q8KA70, PUR9_BUCAP;  
B8D6U7, PUR9_BUCAT;  Q89B23, PUR9_BUCBP;  B1YTE2, PUR9_BURA4;  
Q1BZ33, PUR9_BURCA;  B1JVV6, PUR9_BURCC;  A0K4L7, PUR9_BURCH;  
B4EES4, PUR9_BURCJ;  Q0BI80, PUR9_BURCM;  A9AH70, PUR9_BURM1;  
A3MP76, PUR9_BURM7;  A2S597, PUR9_BURM9;  Q62HA6, PUR9_BURMA;  
A1V068, PUR9_BURMS;  A3NZ64, PUR9_BURP0;  Q3JNS8, PUR9_BURP1;  
A3NDF2, PUR9_BURP6;  B2JGU1, PUR9_BURP8;  B2SYJ7, PUR9_BURPP;  
Q63QX8, PUR9_BURPS;  Q39JI8, PUR9_BURS3;  Q2SZ52, PUR9_BURTA;  
A4JBL5, PUR9_BURVG;  Q13UC4, PUR9_BURXL;  B9MS89, PUR9_CALBD;  
A4XKZ2, PUR9_CALS8;  A7ZCZ7, PUR9_CAMC1;  A7GYY6, PUR9_CAMC5;  
A8FM07, PUR9_CAMJ8;  A7H375, PUR9_CAMJD;  Q9PNY2, PUR9_CAMJE;  
A1VZU4, PUR9_CAMJJ;  Q5HUK6, PUR9_CAMJR;  Q9ABY4, PUR9_CAUCR;  
Q11CT4, PUR9_CHESB;  P31335, PUR9_CHICK;  A9WEK8, PUR9_CHLAA;  
Q3ATZ1, PUR9_CHLCH;  B3EEI0, PUR9_CHLL2;  B3QQA5, PUR9_CHLP8;  
B3ELV3, PUR9_CHLPB;  A1BE85, PUR9_CHLPD;  B3QS62, PUR9_CHLT3;  
Q8KFK6, PUR9_CHLTE;  Q7P0M1, PUR9_CHRVO;  A8AKS0, PUR9_CITK8;  
Q97J91, PUR9_CLOAB;  A7FXD3, PUR9_CLOB1;  C3L2U9, PUR9_CLOB6;  
A6LSB3, PUR9_CLOB8;  B2V3C3, PUR9_CLOBA;  B2TN76, PUR9_CLOBB;  
A5I5V9, PUR9_CLOBH;  C1FV76, PUR9_CLOBJ;  B1IL57, PUR9_CLOBK;  
A7GH96, PUR9_CLOBL;  B1KZ55, PUR9_CLOBM;  B8I490, PUR9_CLOCE;  
B9E4K6, PUR9_CLOK1;  A5N0Q0, PUR9_CLOK5;  A0Q1J0, PUR9_CLONN;  
Q0TTB0, PUR9_CLOP1;  Q8XMK2, PUR9_CLOPE;  Q0SV48, PUR9_CLOPS;  
Q892X3, PUR9_CLOTE;  A3DEU9, PUR9_CLOTH;  Q489F4, PUR9_COLP3;  
C3PF03, PUR9_CORA7;  Q9RHX6, PUR9_CORAM;  Q6NID8, PUR9_CORDI;  
Q8FR29, PUR9_COREF;  A4QCK4, PUR9_CORGB;  Q8NS21, PUR9_CORGL;  
A7MJ89, PUR9_CROS8;  Q0KEC0, PUR9_CUPNH;  Q475R4, PUR9_CUPPJ;  
B2AH76, PUR9_CUPTR;  B8HPG4, PUR9_CYAP4;  B7KGS0, PUR9_CYAP7;  
B7K3N8, PUR9_CYAP8;  C1CWJ7, PUR9_DEIDV;  Q1J119, PUR9_DEIGD;  
Q9RW01, PUR9_DEIRA;  B8FP05, PUR9_DESHD;  Q24QH6, PUR9_DESHY;  
Q86L14, PUR9_DICDI;  A8LMD0, PUR9_DINSH;  A7ZUM3, PUR9_ECO24;  
B7UPG1, PUR9_ECO27;  B7MIZ2, PUR9_ECO45;  B7LAV3, PUR9_ECO55;  
Q8X611, PUR9_ECO57;  B5Z0A3, PUR9_ECO5E;  B7NRT9, PUR9_ECO7I;  
B7MRD0, PUR9_ECO81;  B7M7R5, PUR9_ECO8A;  C5A0U7, PUR9_ECOBW;  
B1XC09, PUR9_ECODH;  A8A7A6, PUR9_ECOHS;  A1AIH7, PUR9_ECOK1;  
Q0TA59, PUR9_ECOL5;  Q8FB68, PUR9_ECOL6;  B1IUP1, PUR9_ECOLC;  
P15639, PUR9_ECOLI;  B7NFU7, PUR9_ECOLU;  B6I5L8, PUR9_ECOSE;  
B1LPG6, PUR9_ECOSM;  Q1R5X1, PUR9_ECOUT;  B2KCF7, PUR9_ELUMP;  
Q833Z3, PUR9_ENTFA;  B2VG81, PUR9_ERWT9;  B7LUJ6, PUR9_ESCF3;  
Q8REV6, PUR9_FUSNN;  B5EBF9, PUR9_GEOBB;  B9M4Q6, PUR9_GEODF;  
B3E7F6, PUR9_GEOLS;  Q39RK1, PUR9_GEOMG;  Q74FJ9, PUR9_GEOSL;  
C6E5Z3, PUR9_GEOSM;  A5G879, PUR9_GEOUR;  P43852, PUR9_HAEIN;  
B0TEC5, PUR9_HELMI;  A4G1U6, PUR9_HERAR;  Q0I557, PUR9_HISS1;  
B0UWT1, PUR9_HISS2;  P31939, PUR9_HUMAN;  A6SUQ1, PUR9_JANMA;  
Q28K03, PUR9_JANSC;  B5XYD2, PUR9_KLEP3;  A6TGR3, PUR9_KLEP7;  
Q5FIV5, PUR9_LACAC;  Q037V3, PUR9_LACC3;  B3WF93, PUR9_LACCB;  
Q1G9G2, PUR9_LACDA;  Q049M1, PUR9_LACDB;  Q9CFG0, PUR9_LACLA;  
A2RJY0, PUR9_LACLM;  Q02Y66, PUR9_LACLS;  Q88U29, PUR9_LACPL;  
A5VHU2, PUR9_LACRD;  B2G5C2, PUR9_LACRJ;  Q1WU55, PUR9_LACS1;  
Q38XW3, PUR9_LACSS;  C1D6F1, PUR9_LARHH;  Q6AD62, PUR9_LEIXX;  
B0SGW3, PUR9_LEPBA;  Q04T56, PUR9_LEPBJ;  Q051H8, PUR9_LEPBL;  
B0SQ10, PUR9_LEPBP;  Q72RT5, PUR9_LEPIC;  Q8F3W6, PUR9_LEPIN;  
B1MY42, PUR9_LEUCK;  Q03Y85, PUR9_LEUMM;  Q92AP3, PUR9_LISIN;  
C1KW64, PUR9_LISMC;  Q71YQ3, PUR9_LISMF;  B8DDZ2, PUR9_LISMH;  
Q8Y6C5, PUR9_LISMO;  A0AJL9, PUR9_LISW6;  B1HTV8, PUR9_LYSSC;  
B9EAZ2, PUR9_MACCJ;  A0LDB0, PUR9_MAGSM;  Q1H4G7, PUR9_METFK;  
B0JL55, PUR9_MICAN;  Q2RGU9, PUR9_MOOTA;  Q9CWJ9, PUR9_MOUSE;  
P67542, PUR9_MYCBO;  A1KH91, PUR9_MYCBP;  C1ALU3, PUR9_MYCBT;  
B8ZU05, PUR9_MYCLB;  Q9Z5H5, PUR9_MYCLE;  B2HEC3, PUR9_MYCMM;  
Q9RAJ5, PUR9_MYCPA;  A3Q5N7, PUR9_MYCSJ;  A1UL88, PUR9_MYCSK;  
Q1B3W0, PUR9_MYCSS;  A5U0Z7, PUR9_MYCTA;  P9WHM6, PUR9_MYCTO;  
P9WHM7, PUR9_MYCTU;  A0PWC5, PUR9_MYCUA;  Q1D898, PUR9_MYXXD;  
B2A5W1, PUR9_NATTJ;  Q5F6T1, PUR9_NEIG1;  B4RP71, PUR9_NEIG2;  
A9M4I2, PUR9_NEIM0;  Q9JUQ8, PUR9_NEIMA;  Q9JZM7, PUR9_NEIMB;  
A1KTP9, PUR9_NEIMF;  Q3JC90, PUR9_NITOC;  A1SMP8, PUR9_NOCSJ;  
B2IX54, PUR9_NOSP7;  Q8YSJ2, PUR9_NOSS1;  Q8CXK7, PUR9_OCEIH;  
A6WXV3, PUR9_OCHA4;  Q04EU6, PUR9_OENOB;  A1B5K8, PUR9_PARDP;  
A7HSQ6, PUR9_PARL1;  P57828, PUR9_PASMU;  Q6DAL2, PUR9_PECAS;  
C6DHT5, PUR9_PECCP;  Q03E83, PUR9_PEDPA;  Q3A2D6, PUR9_PELCD;  
Q3B5R1, PUR9_PELLD;  B4SDT6, PUR9_PELPB;  A1AS76, PUR9_PELPD;  
Q18CW0, PUR9_PEPD6;  C0QRH2, PUR9_PERMH;  A9BIX9, PUR9_PETMO;  
Q7N954, PUR9_PHOLL;  B1XS23, PUR9_POLNS;  A4T025, PUR9_POLSQ;  
Q5R5C2, PUR9_PONAB;  B4S3H9, PUR9_PROA2;  Q6A6Y8, PUR9_PROAC;  
A3PAY7, PUR9_PROM0;  A2C098, PUR9_PROM1;  A8G2S6, PUR9_PROM2;  
A2CCK6, PUR9_PROM3;  A9BDN8, PUR9_PROM4;  A2BUP7, PUR9_PROM5;  
Q31CR6, PUR9_PROM9;  Q7VDS0, PUR9_PROMA;  B4EYT2, PUR9_PROMH;  
Q7TUM7, PUR9_PROMM;  Q7TUG1, PUR9_PROMP;  A2BP65, PUR9_PROMS;  
Q46HA8, PUR9_PROMT;  A4SDE6, PUR9_PROVI;  A6VCW0, PUR9_PSEA7;  
B7V1R6, PUR9_PSEA8;  Q02FG6, PUR9_PSEAB;  Q9HUV9, PUR9_PSEAE;  
Q1I4C1, PUR9_PSEE4;  Q4KIX5, PUR9_PSEF5;  C3K6E0, PUR9_PSEFS;  
Q3IIC3, PUR9_PSEHT;  A4XQ60, PUR9_PSEMY;  A5W9K7, PUR9_PSEP1;  
B0KJZ6, PUR9_PSEPG;  Q88DK3, PUR9_PSEPK;  B1J5T3, PUR9_PSEPW;  
Q87VR9, PUR9_PSESM;  A4VPK9, PUR9_PSEU5;  Q4FRN8, PUR9_PSYA2;  
Q1QA75, PUR9_PSYCK;  A1SZJ2, PUR9_PSYIN;  A5WFX4, PUR9_PSYWF;  
Q1LRB3, PUR9_RALME;  B2UFL5, PUR9_RALPJ;  Q8Y232, PUR9_RALSO;  
O35567, PUR9_RAT;  B3PS36, PUR9_RHIE6;  Q2K2T6, PUR9_RHIEC;  
Q1MA35, PUR9_RHIL3;  Q98ES7, PUR9_RHILO;  B5ZV31, PUR9_RHILW;  
Q92KX6, PUR9_RHIME;  C3MAR5, PUR9_RHISN;  Q7UKJ8, PUR9_RHOBA;  
Q2RN46, PUR9_RHORT;  A3PNE9, PUR9_RHOS1;  Q3IYU8, PUR9_RHOS4;  
A4WWQ0, PUR9_RHOS5;  B9KP36, PUR9_RHOSK;  Q16CE0, PUR9_ROSDO;  
Q5LN38, PUR9_RUEPO;  Q1GKJ2, PUR9_RUEST;  B5F1I9, PUR9_SALA4;  
A9MHC3, PUR9_SALAR;  B5FQM1, PUR9_SALDC;  B5QYG1, PUR9_SALEP;  
B5RFH8, PUR9_SALG2;  B4TDF3, PUR9_SALHS;  B4T108, PUR9_SALNS;  
Q5PKA9, PUR9_SALPA;  A9N0L8, PUR9_SALPB;  C0Q2T8, PUR9_SALPC;  
B5BJS5, PUR9_SALPK;  B4TQL6, PUR9_SALSV;  Q8Z335, PUR9_SALTI;  
P26978, PUR9_SALTY;  O74928, PUR9_SCHPO;  A8G8G3, PUR9_SERP5;  
A1S2J9, PUR9_SHEAM;  Q12IP4, PUR9_SHEDO;  Q088G0, PUR9_SHEFN;  
B0TR91, PUR9_SHEHH;  A3QII0, PUR9_SHELP;  Q8EJM1, PUR9_SHEON;  
A8GZM3, PUR9_SHEPA;  B8CTW4, PUR9_SHEPW;  A8FQD4, PUR9_SHESH;  
B1KNA0, PUR9_SHEWM;  B2TWJ3, PUR9_SHIB3;  Q31TZ1, PUR9_SHIBS;  
Q32AH9, PUR9_SHIDS;  Q0SXZ4, PUR9_SHIF8;  Q83IR9, PUR9_SHIFL;  
Q3YUX8, PUR9_SHISS;  A6UED3, PUR9_SINMW;  Q2NWQ7, PUR9_SODGM;  
A9GIT1, PUR9_SORC5;  A6U0P1, PUR9_STAA2;  Q2FI05, PUR9_STAA3;  
Q2FZI6, PUR9_STAA8;  A5IRW0, PUR9_STAA9;  Q2YX50, PUR9_STAAB;  
Q5HH11, PUR9_STAAC;  A6QFT1, PUR9_STAAE;  P67543, PUR9_STAAM;  
P67544, PUR9_STAAN;  Q6GI11, PUR9_STAAR;  Q6GAE0, PUR9_STAAS;  
Q8NX88, PUR9_STAAW;  B9DQ42, PUR9_STACT;  Q5HQ97, PUR9_STAEQ;  
Q8CT27, PUR9_STAES;  Q4L582, PUR9_STAHJ;  Q49WJ7, PUR9_STAS1;  
Q3K3Z7, PUR9_STRA1;  P67545, PUR9_STRA3;  P67546, PUR9_STRA5;  
Q9KY50, PUR9_STRCO;  C0MB61, PUR9_STRE4;  A8AUA2, PUR9_STRGC;  
B4SL92, PUR9_STRM5;  B2FJP9, PUR9_STRMK;  Q8DWK8, PUR9_STRMU;  
Q04N19, PUR9_STRP2;  P0DD60, PUR9_STRP3;  B5E5J9, PUR9_STRP4;  
Q5XEF2, PUR9_STRP6;  C1C9V4, PUR9_STRP7;  Q8P310, PUR9_STRP8;  
Q1JE78, PUR9_STRPB;  Q1JP34, PUR9_STRPC;  Q1JJ80, PUR9_STRPD;  
Q1J934, PUR9_STRPF;  B1I7V8, PUR9_STRPI;  B8ZJN3, PUR9_STRPJ;  
Q48VY9, PUR9_STRPM;  Q97T99, PUR9_STRPN;  P0DD61, PUR9_STRPQ;  
B5XJ20, PUR9_STRPZ;  Q8DRM1, PUR9_STRR6;  A4VYK5, PUR9_STRS2;  
C0MC89, PUR9_STRS7;  Q9F1T4, PUR9_STRSU;  A4VSB5, PUR9_STRSY;  
Q03MZ6, PUR9_STRTD;  B9DSR6, PUR9_STRU0;  C1CBM7, PUR9_STRZJ;  
C1CHW2, PUR9_STRZP;  C1CNS9, PUR9_STRZT;  Q67KG3, PUR9_SYMTH;  
Q31R91, PUR9_SYNE7;  A5GIF4, PUR9_SYNPW;  Q7TTX6, PUR9_SYNPX;  
Q0IDE8, PUR9_SYNS3;  Q3B083, PUR9_SYNS9;  Q3AN13, PUR9_SYNSC;  
Q0AW31, PUR9_SYNWW;  P74741, PUR9_SYNY3;  Q8DIN5, PUR9_THEEB;  
Q9X0X6, PUR9_THEMA;  B0KBQ1, PUR9_THEP3;  B0K3Q8, PUR9_THEPX;  
Q8RC55, PUR9_THETN;  B5YLE5, PUR9_THEYD;  Q31II8, PUR9_THICR;  
C4LA41, PUR9_TOLAT;  Q116T4, PUR9_TRIEI;  C5CL84, PUR9_VARPS;  
A5F3U8, PUR9_VIBC3;  A7MXG0, PUR9_VIBCB;  Q9KV80, PUR9_VIBCH;  
C3LQN2, PUR9_VIBCM;  Q5E257, PUR9_VIBF1;  B5FC70, PUR9_VIBFM;  
Q87KT0, PUR9_VIBPA;  B7VM57, PUR9_VIBSL;  Q8DD06, PUR9_VIBVU;  
Q7MGT5, PUR9_VIBVY;  Q8D244, PUR9_WIGBR;  Q8PQ19, PUR9_XANAC;  
Q3BY85, PUR9_XANC5;  Q4UZD2, PUR9_XANC8;  B0RN27, PUR9_XANCB;  
Q8PD47, PUR9_XANCP;  Q2P866, PUR9_XANOM;  B2SRB2, PUR9_XANOP;  
Q5H5H7, PUR9_XANOR;  B2I4L7, PUR9_XYLF2;  Q9PC10, PUR9_XYLFA;  
B0U7A0, PUR9_XYLFM;  Q87D58, PUR9_XYLFT;  A1JIJ7, PUR9_YERE8;  
A7FNG6, PUR9_YERP3;  Q1C1V9, PUR9_YERPA;  B2K130, PUR9_YERPB;  
Q8ZAR3, PUR9_YERPE;  A9R8E1, PUR9_YERPG;  Q1CN60, PUR9_YERPN;  
A4TS14, PUR9_YERPP;  Q66FN5, PUR9_YERPS;  B1JJL6, PUR9_YERPY;  

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