ENZYME entry: EC 2.3.1.160

Accepted Name
Vinorine synthase.
Reaction catalysed
Acetyl-CoA + 16-epivellosimine <=> CoA + vinorine
Comment(s)
  • The reaction proceeds in two stages.
  • The indole nitrogen of 16-epivellosimine interacts with its aldehyde group giving an hydroxy-substituted new ring.
  • This alcohol is then acetylated.
  • Also acts on gardneral (11-methoxy-16-epivellosimine).
  • Generates the ajmalan skeleton, which forms part of the route to ajmaline.
Cross-references
BRENDA2.3.1.160
EC2PDB2.3.1.160
ExplorEnz2.3.1.160
PRIAM enzyme-specific profiles2.3.1.160
KEGG Ligand Database for Enzyme Nomenclature2.3.1.160
IUBMB Enzyme Nomenclature2.3.1.160
IntEnz2.3.1.160
MEDLINEFind literature relating to 2.3.1.160
MetaCyc2.3.1.160
UniProtKB/Swiss-Prot
Q70PR7, VINSY_RAUSE

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.1.-
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