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ENZYME

ENZYME entry: EC 2.3.1.164

Accepted Name
isopenicillin-N N-acyltransferase
Alternative Name(s)
acyl-coenzyme A:6-aminopenicillanic-acid-acyltransferase
acyl-coenzyme A:isopenicillin N acyltransferase
isopenicillin N:acyl-CoA acyltransferase
Reaction catalysed
H2O + isopenicillin N + phenylacetyl-CoA <=> CoA + H(+) + L-2-aminoadipate + penicillin G
Comment(s)
  • Proceeds by a two stage mechanism via 6-aminopenicillanic acid.
  • Different from EC 3.5.1.11.
Cross-references
BRENDA2.3.1.164
EC2PDB2.3.1.164
ExplorEnz2.3.1.164
PRIAM enzyme-specific profiles2.3.1.164
KEGG Ligand Database for Enzyme Nomenclature2.3.1.164
IUBMB Enzyme Nomenclature2.3.1.164
IntEnz2.3.1.164
MEDLINEFind literature relating to 2.3.1.164
MetaCyc2.3.1.164
Rhea expert-curated reactions2.3.1.164
UniProtKB/Swiss-Prot
P21133, AATA_EMENIP15802, AATA_PENCHB6HLT9, AATA_PENRW

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