ENZYME entry: EC 2.3.1.165

Accepted Name
6-methylsalicylic acid synthase.
Alternative Name(s)
6-MSAS.
MSAS.
Reaction catalysed
Acetyl-CoA + 3 malonyl-CoA + NADPH <=> 6-methylsalicylate + 4 CoA + 3 CO(2) + NADP(+)
Comment(s)
  • A multienzyme complex with a 4'-phosphopantetheine prosthetic group on the acyl carrier protein.
  • It has a similar sequence to vertebrate type I fatty acid synthase.
  • Acetoacetyl-CoA can also act as a starter molecule.
Cross-references
BRENDA2.3.1.165
EC2PDB2.3.1.165
ExplorEnz2.3.1.165
PRIAM enzyme-specific profiles2.3.1.165
KEGG Ligand Database for Enzyme Nomenclature2.3.1.165
IUBMB Enzyme Nomenclature2.3.1.165
IntEnz2.3.1.165
MEDLINEFind literature relating to 2.3.1.165
MetaCyc2.3.1.165
UniProtKB/Swiss-Prot
P22367, MSAS_PENPA;  A1CFL8, PATK_ASPCL;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.1.-
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