ENZYME entry: EC 2.3.1.176

Accepted Name
Propanoyl-CoA C-acyltransferase.
Alternative Name(s)
Peroxisomal thiolase 2.
PTE-2.
SCP(chi).
SCP-X.
Sterol carrier protein-chi.
Sterol carrier protein-X.
Reaction catalysed
3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholanoyl-CoA + propanoyl-CoA <=> CoA + 3-alpha,7-alpha,12-alpha-trihydroxy-24-oxo-5-beta-cholestanoyl-CoA
Comment(s)
  • Also acts on dihydroxy-5-beta-cholestanoyl-CoA and other branched chain acyl-CoA derivatives.
  • Catalyzes the penultimate step in the formation of bile acids.
  • The bile acid moiety is transferred from the acyl-CoA thioester (RCO- SCoA) to either glycine or taurine (NH(2)R') by EC 2.3.1.65.
Cross-references
PROSITEPDOC00092
BRENDA2.3.1.176
EC2PDB2.3.1.176
ExplorEnz2.3.1.176
PRIAM enzyme-specific profiles2.3.1.176
KEGG Ligand Database for Enzyme Nomenclature2.3.1.176
IUBMB Enzyme Nomenclature2.3.1.176
IntEnz2.3.1.176
MEDLINEFind literature relating to 2.3.1.176
MetaCyc2.3.1.176
UniProtKB/Swiss-Prot
P07857, NLTP_BOVIN;  Q07598, NLTP_CHICK;  P22307, NLTP_HUMAN;  
P32020, NLTP_MOUSE;  O62742, NLTP_RABIT;  P11915, NLTP_RAT;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.1.-
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