ID 2.3.1.184 DE Acyl-homoserine-lactone synthase. AN Acyl homoserine lactone synthase. AN Acyl-homoserine lactone synthase. AN Acyl-homoserinelactone synthase. AN Acylhomoserine lactone synthase. AN AHL synthase. AN AHSL synthase. AN Autoinducer synthase. AN Autoinducer synthesis protein. AN N-acyl homoserine lactone synthase. CA An acyl-[acyl-carrier-protein] + S-adenosyl-L-methionine = [acyl-carrier- CA protein] + S-methyl-5'-thioadenosine + an N-acyl-L-homoserine lactone. CC -!- Acyl-homoserine lactones (AHLs) are produced by a number of bacterial CC species and are used by them to regulate the expression of virulence CC genes in a process known as quorum-sensing. CC -!- Each bacterial cell has a basal level of AHL and, once the population CC density reaches a critical level, it triggers AHL-signaling which, CC in turn, initiates the expression of particular virulence genes. CC -!- N-(3-oxohexanoyl)-[acyl-carrier-protein] and hexanoyl-[acyl-carrier- CC protein] are the best substrates. CC -!- The fatty-acyl substrate is derived from fatty-acid biosynthesis CC through acyl-[acyl-carrier-protein] rather than from fatty-acid CC degradation through acyl-CoA. CC -!- S-adenosyl-L-methionine cannot be replaced by methionine, CC S-adenosylhomocysteine, homoserine or homoserine lactone. PR PROSITE; PDOC51186; DR Q44058, AHYI_AERHY ; P70774, ASAI_AERSA ; P33880, CARI_PECCC ; DR P33881, EAGI_ENTAG ; Q46968, ECHI_ERWCH ; P54656, ESAI_ERWST ; DR Q47187, EXPI_DICD3 ; P33882, EXPI_PECCC ; P33883, LASI_PSEAE ; DR P12747, LUXI_VIBFI ; P35328, LUXJ_VIBF1 ; P54298, LUXM_VIBHA ; DR A7MRY3, LUXM_VIBHB ; B7VQM9, LUXM_VIBSL ; Q87NA8, OPAM_VIBPA ; DR Q51522, PHZI_PSECL ; Q51785, PHZI_PSEFL ; P52990, PSYI_PSESZ ; DR O54451, RAII_RHIET ; P54291, RHLI_PSEAE ; O30920, SOLI_RALSL ; DR P58584, SOLI_RALSO ; P52989, SWRI_SERLI ; P33907, TRAI_AGRT5 ; DR P33904, TRAI_RHIRD ; P55394, TRAI_RHISN ; P74945, VANI_VIBAN ; DR Q9FDA3, VANM_VIBAN ; P52988, YENI_YEREN ; O87970, YUKI_YERRU ; //