ID 2.3.1.184 DE acyl-homoserine-lactone synthase. AN acylhomoserine lactone synthase. AN acyl homoserine lactone synthase. AN acyl-homoserinelactone synthase. AN acyl-homoserine lactone synthase. AN AHL synthase. AN AHSL synthase. AN autoinducer synthase. AN autoinducer synthesis protein. AN N-acyl homoserine lactone synthase. CA a fatty acyl-[ACP] + S-adenosyl-L-methionine = an N-acyl-L-homoserine CA lactone + H(+) + holo-[ACP] + S-methyl-5'-thioadenosine. CC -!- Acyl-homoserine lactones (AHLs) are produced by a number of bacterial CC species and are used by them to regulate the expression of virulence CC genes in a process known as quorum-sensing. CC -!- Each bacterial cell has a basal level of AHL and, once the population CC density reaches a critical level, it triggers AHL-signaling which, CC in turn, initiates the expression of particular virulence genes. CC -!- N-(3-oxohexanoyl)-[acyl-carrier-protein] and hexanoyl-[acyl-carrier- CC protein] are the best substrates. CC -!- The fatty-acyl substrate is derived from fatty-acid biosynthesis CC through acyl-[acyl-carrier-protein] rather than from fatty-acid CC degradation through acyl-CoA. CC -!- S-Adenosyl-L-methionine cannot be replaced by methionine, CC S-adenosylhomocysteine, homoserine or homoserine lactone. DR B0FLN1, ABAI_ACIBA ; Q44058, AHYI_AERHY ; A0A0A7XNA3, ANOI_ACINO ; DR P70774, ASAI_AERSA ; P33880, CARI_PECCC ; P33881, EAGI_ENTAG ; DR Q46968, ECHI_DICCH ; P54656, ESAI_PANSE ; Q47187, EXPI_DICD3 ; DR P33882, EXPI_PECPM ; P33883, LASI_PSEAE ; P12747, LUXI_ALIFS ; DR P35328, LUXJ_ALIF1 ; B7VQM9, LUXM_VIBA3 ; A7MRY3, LUXM_VIBC1 ; DR P54298, LUXM_VIBHA ; Q87NA8, OPAM_VIBPA ; Q51522, PHZI_PSECL ; DR Q51785, PHZI_PSEFL ; P52990, PSYI_PSEAJ ; O54451, RAII_RHIET ; DR P54291, RHLI_PSEAE ; P58584, SOLI_RALN1 ; O30920, SOLI_RALSL ; DR P52989, SWRI_SERLI ; P33907, TRAI_AGRFC ; P33904, TRAI_RHIRD ; DR P55394, TRAI_SINFN ; P74945, VANI_VIBAN ; Q9FDA3, VANM_VIBAN ; DR P52988, YENI_YEREN ; O87970, YUKI_YERRU ; //