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ENZYME entry: EC 2.3.1.194

Accepted Name
Acetoacetyl-CoA synthase.
Alternative Name(s)
NphT7.
Reaction catalysed
Acetyl-CoA + malonyl-CoA <=> acetoacetyl-CoA + CoA + CO(2)
Comment(s)
  • The enzyme from the soil bacterium Streptomyces sp. CL190 produces acetoacetyl-CoA to be used for mevalonate production via the mevalonate pathway.
  • Unlike the homologous EC 2.3.1.180 this enzyme does not accept malonyl-[acyl-carrier-protein] as a substrate.
Cross-references
BRENDA2.3.1.194
EC2PDB2.3.1.194
ExplorEnz2.3.1.194
PRIAM enzyme-specific profiles2.3.1.194
KEGG Ligand Database for Enzyme Nomenclature2.3.1.194
IUBMB Enzyme Nomenclature2.3.1.194
IntEnz2.3.1.194
MEDLINEFind literature relating to 2.3.1.194
MetaCyc2.3.1.194
UniProtKB/Swiss-Prot
D7URV0, NPHT7_STRC1

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-