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ENZYME

ENZYME entry: EC 2.3.1.211

Accepted Name
bisdemethoxycurcumin synthase
Alternative Name(s)
curcuminoid synthase
Reaction catalysed
2 4-coumaroyl-CoA + H(+) + H2O + malonyl-CoA <=> bisdemethoxycurcumin + 2 CO2 + 3 CoA
Comment(s)
  • A polyketide synthase characterized from the plant Oryza sativa (rice) that catalyzes the formation of the C6-C7-C6 diarylheptanoid scaffold of bisdemethoxycurcumin.
  • Unlike the process in the plant Curcuma longa (turmeric), where the conversion is carried out via a diketide intermediate by two different enzymes, the diketide intermediate formed by this enzyme remains within the enzyme's cavity and is not released to the environment.
  • Formerly EC 2.3.1.n9.
Cross-references
BRENDA2.3.1.211
EC2PDB2.3.1.211
ExplorEnz2.3.1.211
PRIAM enzyme-specific profiles2.3.1.211
KEGG Ligand Database for Enzyme Nomenclature2.3.1.211
IUBMB Enzyme Nomenclature2.3.1.211
IntEnz2.3.1.211
MEDLINEFind literature relating to 2.3.1.211
MetaCyc2.3.1.211
Rhea expert-curated reactions2.3.1.211
UniProtKB/Swiss-Prot
Q8LIL0, CUS_ORYSJ

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