ENZYME entry: EC 2.3.1.221

Accepted Name
Noranthrone synthase.
Alternative Name(s)
Norsolorinic acid anthrone synthase.
Polyketide synthase A.
Reaction catalysed
7 malonyl-CoA + hexanoyl-[acyl-carrier protein] <=> 7 CoA + norsolorinate anthrone + [acyl-carrier protein] + 7 CO(2) + 2 H(2)O
Comment(s)
  • A multi-domain polyketide synthase involved in the synthesis of aflatoxins in the fungus Aspergillus parasiticus.
  • The hexanoyl starter unit is provided to the acyl-carrier protein (ACP) domain by a dedicated fungal fatty acid synthase.
Cross-references
BRENDA2.3.1.221
EC2PDB2.3.1.221
ExplorEnz2.3.1.221
PRIAM enzyme-specific profiles2.3.1.221
KEGG Ligand Database for Enzyme Nomenclature2.3.1.221
IUBMB Enzyme Nomenclature2.3.1.221
IntEnz2.3.1.221
MEDLINEFind literature relating to 2.3.1.221
MetaCyc2.3.1.221
UniProtKB/Swiss-Prot
Q12053, PKSL1_ASPPA

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-