ID   2.3.1.230
DE   2-heptyl-4(1H)-quinolone synthase.
CA   (2-aminobenzoyl)acetate + H(+) + octanoyl-CoA = 2-heptyl-4(1H)-quinolone
CA   + CO2 + CoA + H2O.
CC   -!- The enzyme, characterized from the bacterium Pseudomonas aeruginosa,
CC       is a heterodimeric complex.
CC   -!- The PqsC subunit acquires an octanoyl group from octanoyl-CoA and
CC       attaches it to an internal cysteine residue.
CC   -!- Together with the PqsB subunit, the proteins catalyze the coupling of
CC       the octanoyl group with (2-aminobenzoyl)acetate, leading to
CC       decarboxylation and dehydration events that result in closure of the
CC       quinoline ring.
DR   Q9I4X1, PQSC_PSEAE ;
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