ENZYME entry: EC 2.3.1.246
Accepted Name | ||||
---|---|---|---|---|
3,5-dihydroxyphenylacetyl-CoA synthase | ||||
Reaction catalysed | ||||
4 H(+) + 4 malonyl-CoA = (3,5-dihydroxyphenyl)acetyl-CoA + 4 CO2 + 3 CoA + H2O | ||||
Comment(s) | ||||
The enzyme, characterized from the bacterium Amycolatopsis mediterranei, is involved in biosynthesis of the nonproteinogenic amino acid (S)-3,5-dihydroxyphenylglycine, a component of the vancomycin-type antibiotic balhimycin. | ||||
Cross-references | ||||
BRENDA | 2.3.1.246 | |||
EC2PDB | 2.3.1.246 | |||
ExplorEnz | 2.3.1.246 | |||
PRIAM enzyme-specific profiles | 2.3.1.246 | |||
KEGG Ligand Database for Enzyme Nomenclature | 2.3.1.246 | |||
IUBMB Enzyme Nomenclature | 2.3.1.246 | |||
IntEnz | 2.3.1.246 | |||
MEDLINE | Find literature relating to 2.3.1.246 | |||
MetaCyc | 2.3.1.246 | |||
Rhea expert-curated reactions | 2.3.1.246 | |||
UniProtKB/Swiss-Prot |
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