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ENZYME

ENZYME entry: EC 2.3.1.277

Accepted Name
2-oxo-3-(phosphooxy)propyl 3-oxoalkanoate synthase
Reaction catalysed
a medium-chain 3-oxoacyl-[ACP] + dihydroxyacetone phosphate <=> a 2-oxo-3-(phosphooxy)propyl medium-chain 3-oxoalkanoate + holo-[ACP]
Comment(s)
The enzyme catalyzes the first committed step in the biosynthesis of gamma-butyrolactone autoregulators that control secondary metabolism and morphological development in Streptomyces bacteria.
Cross-references
BRENDA2.3.1.277
EC2PDB2.3.1.277
ExplorEnz2.3.1.277
PRIAM enzyme-specific profiles2.3.1.277
KEGG Ligand Database for Enzyme Nomenclature2.3.1.277
IUBMB Enzyme Nomenclature2.3.1.277
IntEnz2.3.1.277
MEDLINEFind literature relating to 2.3.1.277
MetaCyc2.3.1.277
Rhea expert-curated reactions2.3.1.277
UniProtKB/Swiss-Prot
B1VN93, AFSA_STRGGP18394, AFSA_STRGRO24738, BARX_STRVG
Q7AKF0, SCBA_STRCO

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