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ENZYME

ENZYME entry: EC 2.3.1.308

Accepted Name
tubulin N-terminal N-acetyltransferase NAT9
Alternative Name(s)
microtubule-associated N-acetyltransferase NAT9
Reaction catalysed
acetyl-CoA + N-terminal L-methionyl-[tubulin] <=> CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-[tubulin]
Comment(s)
  • The enzyme, characterized from the fruit fly (Drosophila melanogaster), acetylates the N-terminal of both alpha- and beta- tubulin.
  • The enzyme acts cotranslationally, and can't act on a preformed tubulin alpha/beta heterodimer.
Cross-references
BRENDA2.3.1.308
EC2PDB2.3.1.308
ExplorEnz2.3.1.308
PRIAM enzyme-specific profiles2.3.1.308
KEGG Ligand Database for Enzyme Nomenclature2.3.1.308
IUBMB Enzyme Nomenclature2.3.1.308
IntEnz2.3.1.308
MEDLINEFind literature relating to 2.3.1.308
MetaCyc2.3.1.308
Rhea expert-curated reactions2.3.1.308
UniProtKB/Swiss-Prot
Q9V9V9, NAT9_DROMEQ9BTE0, NAT9_HUMANQ3UG98, NAT9_MOUSE

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