ID   2.3.1.39
DE   [Acyl-carrier-protein] S-malonyltransferase.
AN   Acyl carrier protein malonyltransferase.
AN   Malonyl coenzyme A-acyl carrier protein transacylase.
AN   Malonyl transacylase.
AN   Malonyl transferase.
AN   Malonyl-CoA-acyl carrier protein transacylase.
AN   Malonyl-CoA/dephospho-CoA acyltransferase.
AN   MCAT.
CA   Malonyl-CoA + [acyl-carrier-protein] = CoA + malonyl-[acyl-carrier-
CA   protein].
CC   -!- Essential, along with EC 2.3.1.38, for the initiation of fatty-acid
CC       biosynthesis in bacteria.
CC   -!- Also provides the malonyl groups for polyketide biosynthesis.
CC   -!- The product of the reaction, malonyl-ACP, is an elongation substrate
CC       in fatty-acid biosynthesis.
CC   -!- In Mycobacterium tuberculosis, holo-ACP (the product of EC 2.7.8.7)
CC       is the preferred substrate.
CC   -!- This enzyme also forms part of the multienzyme complexes EC 4.1.1.88
CC       and EC 4.1.1.89.
CC   -!- Malonylation of ACP is immediately followed by decarboxylation within
CC       the malonate-decarboxylase complex to yield acetyl-ACP,
CC       the catalytically active species of the decarboxylase.
CC   -!- In the enzyme from Klebsiella pneumoniae, methylmalonyl-CoA can also
CC       act as a substrate but acetyl-CoA cannot whereas the enzyme from
CC       Pseudomonas putida can use both as substrates.
CC   -!- The ACP subunit found in fatty-acid biosynthesis contains a
CC       pantetheine-4'-phosphate prosthetic group; that from malonate
CC       decarboxylase also contains pantetheine-4'-phosphate but in the form
CC       of a 2'-(5-triphosphoribosyl)-3'-dephospho-CoA prosthetic group.
DR   A7Z4X8, BAEC_BACA2 ;  A7Z4Y0, BAEE_BACA2 ;  P71019, FABD_BACSU ;
DR   Q8K9J6, FABD_BUCAP ;  Q89AH0, FABD_BUCBP ;  Q8T3L6, FABD_DROME ;
DR   Q8X8I7, FABD_ECO57 ;  P0AAJ0, FABD_ECOL6 ;  P0AAI9, FABD_ECOLI ;
DR   P43712, FABD_HAEIN ;  Q8IVS2, FABD_HUMAN ;  Q8R3F5, FABD_MOUSE ;
DR   P63459, FABD_MYCBO ;  A0R0B2, FABD_MYCS2 ;  P63458, FABD_MYCTU ;
DR   O85140, FABD_SALTY ;  O13698, FABD_SCHPO ;  Q5HGK3, FABD_STAAC ;
DR   Q99UN8, FABD_STAAM ;  Q7A5Z3, FABD_STAAN ;  Q6GHK5, FABD_STAAR ;
DR   Q6G9Y3, FABD_STAAS ;  Q93QD4, FABD_STAAU ;  Q7A124, FABD_STAAW ;
DR   P73242, FABD_SYNY3 ;  Q12283, FABD_YEAST ;  P34731, FAS1_CANAX ;
DR   Q9UUG0, FAS1_SCHPO ;  P34229, FAS1_YARLI ;  P07149, FAS1_YEAST ;
DR   Q71SP7, FAS_BOVIN  ;  P12276, FAS_CHICK  ;  P49327, FAS_HUMAN  ;
DR   P19096, FAS_MOUSE  ;  P12785, FAS_RAT    ;  Q9R9J2, FENF_BACSU ;
DR   O34825, PKSC_BACSU ;  O34787, PKSE_BACSU ;  Q92215, TOXC_COCCA ;
//