ID   2.3.1.39
DE   [acyl-carrier-protein] S-malonyltransferase.
AN   acyl carrier protein malonyltransferase.
AN   malonyl-CoA/dephospho-CoA acyltransferase.
AN   malonyl-CoA-acyl carrier protein transacylase.
AN   malonyl coenzyme A-acyl carrier protein transacylase.
AN   malonyl transacylase.
AN   malonyl transferase.
AN   MCAT.
CA   holo-[ACP] + malonyl-CoA = CoA + malonyl-[ACP].
CC   -!- Essential, along with EC 2.3.1.38, for the initiation of fatty-acid
CC       biosynthesis in bacteria.
CC   -!- Also provides the malonyl groups for polyketide biosynthesis.
CC   -!- The product of the reaction, malonyl-ACP, is an elongation substrate
CC       in fatty-acid biosynthesis.
CC   -!- In Mycobacterium tuberculosis, holo-ACP (the product of EC 2.7.8.7)
CC       is the preferred substrate.
CC   -!- This enzyme also forms part of the multienzyme complexes EC 4.1.1.88
CC       and EC 4.1.1.89.
CC   -!- Malonylation of ACP is immediately followed by decarboxylation within
CC       the malonate-decarboxylase complex to yield acetyl-ACP,
CC       the catalytically active species of the decarboxylase.
CC   -!- In the enzyme from Klebsiella pneumoniae, methylmalonyl-CoA can also
CC       act as a substrate but acetyl-CoA cannot whereas the enzyme from
CC       Pseudomonas putida can use both as substrates.
CC   -!- The ACP subunit found in fatty-acid biosynthesis contains a
CC       pantetheine-4'-phosphate cofactor; that from malonate decarboxylase
CC       also contains pantetheine-4'-phosphate but in the form of a
CC       2'-(5-triphosphoribosyl)-3'-dephospho-CoA cofactor.
DR   Q8TGA1, AFLB_ASPPU ;  Q5AV07, ATNM_EMENI ;  A7Z4X8, BAEC_BACVZ ;
DR   A7Z4Y0, BAEE_BACVZ ;  P71019, FABD_BACSU ;  Q8K9J6, FABD_BUCAP ;
DR   Q89AH0, FABD_BUCBP ;  Q8T3L6, FABD_DROME ;  Q8X8I7, FABD_ECO57 ;
DR   P0AAJ0, FABD_ECOL6 ;  P0AAI9, FABD_ECOLI ;  P43712, FABD_HAEIN ;
DR   Q8IVS2, FABD_HUMAN ;  Q8R3F5, FABD_MOUSE ;  P63459, FABD_MYCBO ;
DR   A0R0B2, FABD_MYCS2 ;  P9WNG4, FABD_MYCTO ;  P9WNG5, FABD_MYCTU ;
DR   O85140, FABD_SALTY ;  O13698, FABD_SCHPO ;  Q5HGK3, FABD_STAAC ;
DR   Q99UN8, FABD_STAAM ;  Q7A5Z3, FABD_STAAN ;  Q6GHK5, FABD_STAAR ;
DR   Q6G9Y3, FABD_STAAS ;  Q93QD4, FABD_STAAU ;  Q7A124, FABD_STAAW ;
DR   P73242, FABD_SYNY3 ;  Q12283, FABD_YEAST ;  P34731, FAS1_CANAX ;
DR   Q9UUG0, FAS1_SCHPO ;  P34229, FAS1_YARLI ;  P07149, FAS1_YEAST ;
DR   Q71SP7, FAS_BOVIN  ;  P12276, FAS_CHICK  ;  P49327, FAS_HUMAN  ;
DR   P19096, FAS_MOUSE  ;  P12785, FAS_RAT    ;  Q9R9J2, FENF_BACIU ;
DR   I1S489, GRA7_GIBZE ;  M2XHU6, HEXB_DOTSN ;  Q2TXG3, ORYB_ASPOR ;
DR   A0A1U8QK63, PKIC_EMENI ;  O34825, PKSC_BACSU ;  O34787, PKSE_BACSU ;
DR   Q00706, STCK_EMENI ;  Q2T4N0, THAF_BURTA ;  Q92215, TOXC_COCCA ;
//