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|Beta-ketoacyl-[acyl-carrier-protein] synthase I.
|3-ketoacyl-acyl carrier protein synthase.|
|Acyl-malonyl acyl carrier protein-condensing enzyme.|
|Beta-ketoacyl acyl carrier protein synthase.|
|Beta-ketoacyl-[acyl carrier protein] synthase.|
|Beta-ketoacyl-ACP synthase I.|
|Beta-ketoacyl-acyl carrier protein synthetase.|
|Fatty acid condensing enzyme.|
|Acyl-[acyl-carrier-protein] + malonyl-[acyl-carrier-protein] <=> 3-oxoacyl-[acyl-carrier-protein] + CO(2) + [acyl-carrier-protein]|
- Responsible for the chain-elongation step of dissociated (type II)
fatty-acid biosynthesis, i.e. the addition of two C atoms to the
- Escherichia coli mutants that lack this enzyme are deficient in
unsaturated fatty acids.
- Can use fatty acyl thioesters of ACP (C(2) to C(16)) as substrates,
as well as fatty acyl thioesters of Co-A (C(4) to C(16)).
- The substrate specificity is very similar to that of EC 188.8.131.52
with the exception that the latter enzyme is far more active with
palmitoleoyl-ACP (C(16)-Delta(9)) as substrate, allowing the organism
to regulate its fatty-acid composition with changes in temperature.
|PRIAM enzyme-specific profiles||184.108.40.206|
|KEGG Ligand Database for Enzyme Nomenclature||220.127.116.11|
|IUBMB Enzyme Nomenclature||18.104.22.168|
|MEDLINE||Find literature relating to 22.214.171.124|
|Q8TGA2, AFLA_ASPPU; ||P39525, CEM1_YEAST; ||P63455, FAB1_MYCBO; |
|Q9CBS7, FAB1_MYCLE; ||H8ESN0, FAB1_MYCTE; ||P9WQD8, FAB1_MYCTO; |
|P9WQD9, FAB1_MYCTU; ||P63457, FAB2_MYCBO; ||O69473, FAB2_MYCLE; |
|P9WQD6, FAB2_MYCTO; ||P9WQD7, FAB2_MYCTU; ||P57193, FABB_BUCAI; |
|Q8KA28, FABB_BUCAP; ||Q89AY4, FABB_BUCBP; ||P0A954, FABB_ECOL6; |
|P0A953, FABB_ECOLI; ||P43710, FABB_HAEIN; ||Q02K94, FABB_PSEAB; |
|P43098, FAS2_CANAX; ||G8BAW7, FAS2_CANPC; ||P78615, FAS2_EMEND; |
|Q5B7V0, FAS2_EMENI; ||Q765N2, FAS2_LACKL; ||P15368, FAS2_PENPA; |
|Q10289, FAS2_SCHPO; ||P19097, FAS2_YEAST; ||Q71SP7, FAS_BOVIN; |
|P12276, FAS_CHICK; ||P49327, FAS_HUMAN; ||P19096, FAS_MOUSE; |
|P12785, FAS_RAT; ||P52410, KASC1_ARATH; ||P23902, KASC1_HORVU; |
|Q9C9P4, KASC2_ARATH; ||Q8L3X9, KASM_ARATH; ||Q7TXK8, MSL7_MYCBO; |
|B2HIL7, MSL7_MYCMM; ||Q0VCA7, OXSM_BOVIN; ||Q9NWU1, OXSM_HUMAN; |
|Q9D404, OXSM_MOUSE; ||O94297, OXSM_SCHPO; ||Q7TXM0, PPSA_MYCBO; |
|P9WQE6, PPSA_MYCTO; ||P9WQE7, PPSA_MYCTU; ||Q7TXL9, PPSB_MYCBO; |
|P9WQE4, PPSB_MYCTO; ||P9WQE5, PPSB_MYCTU; ||Q7TXL8, PPSC_MYCBO; |
|P96202, PPSC_MYCTU; ||Q7TXL7, PPSD_MYCBO; ||P9WQE2, PPSD_MYCTO; |
|P9WQE3, PPSD_MYCTU; ||Q7TXL6, PPSE_MYCBO; ||P9WQE0, PPSE_MYCTO; |
|P9WQE1, PPSE_MYCTU; |
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