ENZYME entry: EC 2.3.1.81
| Accepted Name |
|---|
| Aminoglycoside N(3')-acetyltransferase.
|
| Alternative Name(s) |
|---|
| Gentamicin-(3)-N-acetyltransferase. |
| Reaction catalysed |
|---|
| Acetyl-CoA + a 2-deoxystreptamine antibiotic <=> CoA + N(3')-acetyl-2-deoxystreptamine antibiotic |
| Comment(s) |
|---|
- A wide range of antibiotics containing the 2-deoxystreptamine ring
can act as acceptor, including gentamicin, kanamycin, tobramycin,
neomycin and apramycin.
- Different from EC 2.3.1.60.
|
| Cross-references |
|---|
| BRENDA | 2.3.1.81 |
| EC2PDB | 2.3.1.81 |
| ExplorEnz | 2.3.1.81 |
| PRIAM enzyme-specific profiles | 2.3.1.81 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.3.1.81 |
| IUBMB Enzyme Nomenclature | 2.3.1.81 |
| IntEnz | 2.3.1.81 |
| MEDLINE | Find literature relating to 2.3.1.81 |
| MetaCyc | 2.3.1.81 |
| UniProtKB/Swiss-Prot |
| P13246, AAC31_SALSP; | P0A255, AAC32_SALSP; | Q01515, AAC3_SERMA; |
| P29807, AACC2_ACIBA; | P0A256, AACC3_ENTCL; | P29808, AACC3_PSEAI; |
| P08988, AACC4_SALSP; | P30180, AACC7_STRRY; | P29809, AACC8_STRFR; |
| P29810, AACC9_MICCH; |
|
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