ENZYME entry: EC 2.3.1.81

Accepted Name
Aminoglycoside N(3')-acetyltransferase.
Alternative Name(s)
Gentamicin-(3)-N-acetyltransferase.
Reaction catalysed
Acetyl-CoA + a 2-deoxystreptamine antibiotic <=> CoA + N(3')-acetyl-2-deoxystreptamine antibiotic
Comment(s)
  • A wide range of antibiotics containing the 2-deoxystreptamine ring can act as acceptor, including gentamicin, kanamycin, tobramycin, neomycin and apramycin.
  • Different from EC 2.3.1.60.
Cross-references
BRENDA2.3.1.81
EC2PDB2.3.1.81
ExplorEnz2.3.1.81
PRIAM enzyme-specific profiles2.3.1.81
KEGG Ligand Database for Enzyme Nomenclature2.3.1.81
IUBMB Enzyme Nomenclature2.3.1.81
IntEnz2.3.1.81
MEDLINEFind literature relating to 2.3.1.81
MetaCyc2.3.1.81
UniProtKB/Swiss-Prot
P13246, AAC31_SALSP;  P0A255, AAC32_SALSP;  Q01515, AAC3_SERMA;  
P29807, AACC2_ACIBA;  P0A256, AACC3_ENTCL;  P29808, AACC3_PSEAI;  
P08988, AACC4_SALSP;  P30180, AACC7_STRRY;  P29809, AACC8_STRFR;  
P29810, AACC9_MICCH;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.1.-
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