ENZYME entry: EC 2.3.1.88

Accepted Name
Peptide alpha-N-acetyltransferase.
Alternative Name(s)
Amino-terminal amino acid-acetylating enzyme.
Beta-endorphin acetyltransferase.
N(alpha)-acetyltransferase.
NAT.
Peptide acetyltransferase.
Protein N-terminal acetyltransferase.
Reaction catalysed
Acetyl-CoA + peptide <=> N(alpha)-acetylpeptide + CoA
Comment(s)
Acetylates N-terminal alanine, serine, methionine and glutamate residues in a number of peptides and proteins, including beta- endorphin, corticotropins and melanotropin (cf. EC 2.3.1.108).
Cross-references
BRENDA2.3.1.88
EC2PDB2.3.1.88
ExplorEnz2.3.1.88
PRIAM enzyme-specific profiles2.3.1.88
KEGG Ligand Database for Enzyme Nomenclature2.3.1.88
IUBMB Enzyme Nomenclature2.3.1.88
IntEnz2.3.1.88
MEDLINEFind literature relating to 2.3.1.88
MetaCyc2.3.1.88
UniProtKB/Swiss-Prot
Q9UTI3, ARD1_SCHPO;  P07347, ARD1_YEAST;  Q2KI14, NAA10_BOVIN;  
P41227, NAA10_HUMAN;  Q9QY36, NAA10_MOUSE;  Q9BSU3, NAA11_HUMAN;  
Q3UX61, NAA11_MOUSE;  Q4V8K3, NAA11_RAT;  Q58ED9, NAA20_DANRE;  
P61599, NAA20_HUMAN;  Q2PFM2, NAA20_MACFA;  P61600, NAA20_MOUSE;  
Q7ZXR3, NAA20_XENLA;  Q6P632, NAA20_XENTR;  Q147X3, NAA30_HUMAN;  
Q8CES0, NAA30_MOUSE;  O74311, NAA30_SCHPO;  Q03503, NAA30_YEAST;  
Q17QK9, NAA60_BOVIN;  A3KPA3, NAA60_DANRE;  Q95SX8, NAA60_DROME;  
Q9H7X0, NAA60_HUMAN;  Q9DBU2, NAA60_MOUSE;  Q3MHC1, NAA60_RAT;  
A8E5V7, NAA60_XENTR;  P37293, NAT2_YEAST;  Q06504, NAT3_YEAST;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.1.-
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