ID   2.3.1.9
DE   acetyl-CoA C-acetyltransferase.
AN   acetoacetyl-CoA thiolase.
CA   2 acetyl-CoA = acetoacetyl-CoA + CoA.
CC   -!- The enzyme, found in both eukaryotes and prokaryotes, catalyzes the
CC       Claisen condensation of an acetyl-CoA and an acyl-CoA (often another
CC       acetyl-CoA), leading to the formation of an acyl-CoA that is longer
CC       by two carbon atoms.
CC   -!- The reaction starts with the acylation of a nucleophilic cysteine at
CC       the active site, usually by acetyl-CoA but potentially by a different
CC       acyl-CoA, with concomitant release of CoA.
CC   -!- In the second step the acyl group is transferred to an acetyl-CoA
CC       molecule. cf. EC 2.3.1.16.
DR   Q9FIK7, AACT1_ARATH;  Q8S4Y1, ACCT2_ARATH;  P76461, ATOB_ECOLI ;
DR   P44873, ATOB_HAEIN ;  Q9I2A8, ATOB_PSEAE ;  Q0KBP1, BKTB_CUPNH ;
DR   B0XMC1, ER10A_ASPFC;  Q4WLA8, ER10A_ASPFU;  I1RMA2, ER10A_GIBZE;
DR   B0YA65, ER10B_ASPFC;  Q4WCL5, ER10B_ASPFU;  I1RY81, ER10B_GIBZE;
DR   A0A1D8PH52, ERG10_CANAL;  P10551, ERG10_SACMO;  Q9UQW6, ERG10_SCHPO;
DR   P41338, ERG10_YEAST;  P66927, FADA4_MYCBO;  P46707, FADA4_MYCLE;
DR   A0R1Y7, FADA4_MYCS2;  P9WG68, FADA4_MYCTO;  P9WG69, FADA4_MYCTU;
DR   Q12598, THIA_CANTR ;  Q04677, THIB_CANTR ;  Q9BWD1, THIC_HUMAN ;
DR   Q8CAY6, THIC_MOUSE ;  Q5XI22, THIC_RAT   ;  Q921H8, THIKA_MOUSE;
DR   P21775, THIKA_RAT  ;  Q8VCH0, THIKB_MOUSE;  P07871, THIKB_RAT  ;
DR   P09110, THIK_HUMAN ;  Q86AD9, THIL1_DICDI;  Q6NU46, THILA_XENLA;
DR   Q6GN02, THILB_XENLA;  P45369, THIL_ALLVD ;  Q29RZ0, THIL_BOVIN ;
DR   Q9ZHI1, THIL_CHRVO ;  P14611, THIL_CUPNH ;  Q6AZA0, THIL_DANRE ;
DR   P24752, THIL_HUMAN ;  Q8HXY6, THIL_MACFA ;  Q8QZT1, THIL_MOUSE ;
DR   P54810, THIL_PARDE ;  P14610, THIL_PIG   ;  P17764, THIL_RAT   ;
DR   P50174, THIL_RHIME ;  P07097, THIL_SHIZO ;  P73825, THIL_SYNY3 ;
DR   P45363, THIL_THIVI ;  Q5BKN8, THIL_XENTR ;  Q6L8K7, THIL_YARLI ;
DR   Q3T0R7, THIM_BOVIN ;  P42765, THIM_HUMAN ;  Q8BWT1, THIM_MOUSE ;
DR   Q5RES5, THIM_PONAB ;  P13437, THIM_RAT   ;  P45359, THLA_CLOAB ;
DR   Q18AR0, THLA_CLOD6 ;  P45362, THLA_CLODI ;  P81347, THLA_CLOPA ;
DR   Q2FJQ9, THLA_STAA3 ;  Q2G124, THLA_STAA8 ;  Q2YVF5, THLA_STAAB ;
DR   Q5HIU0, THLA_STAAC ;  Q99WM3, THLA_STAAM ;  Q7A7L2, THLA_STAAN ;
DR   Q6GJW4, THLA_STAAR ;  Q6GCB8, THLA_STAAS ;  Q8NY95, THLA_STAAW ;
DR   Q5HS07, THLA_STAEQ ;  Q8CQN7, THLA_STAES ;  Q0AVM3, THLA_SYNWW ;
DR   P45855, THL_BACSU  ;  Q46939, YQEF_ECOLI ;
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