ID   2.3.1.97
DE   glycylpeptide N-tetradecanoyltransferase.
AN   peptide N-myristoyltransferase.
AN   peptide N-tetradecanoyltransferase.
CA   N-terminal glycyl-[protein] + tetradecanoyl-CoA = CoA + H(+) +
CA   N-tetradecanoylglycyl-[protein].
CC   -!- The enzyme catalyzes the transfer of myristic acid from myristoyl-CoA
CC       to the amino group of the N-terminal glycine residue in a variety of
CC       eukaryotic proteins.
CC   -!- It uses an ordered Bi Bi reaction in which myristoyl-CoA binds to the
CC       enzyme prior to the binding of the peptide substrate, and CoA release
CC       precedes the release of the myristoylated peptide.
CC   -!- The enzyme from yeast is profoundly affected by amino acids further
CC       from the N-terminus, and is particularly stimulated by a serine
CC       residue at position 5.
DR   Q9LTR9, NMT1_ARATH ;  P31717, NMT1_BOVIN ;  P30419, NMT1_HUMAN ;
DR   O70310, NMT1_MOUSE ;  Q5RAF3, NMT1_PONAB ;  Q8K1Q0, NMT1_RAT   ;
DR   Q94L32, NMT2_ARATH ;  Q9N181, NMT2_BOVIN ;  A7YT82, NMT2_DANRE ;
DR   O60551, NMT2_HUMAN ;  O70311, NMT2_MOUSE ;  P34763, NMT_AJECA  ;
DR   Q9EMI7, NMT_AMEPV  ;  Q9UVX3, NMT_ASPFU  ;  P46548, NMT_CAEEL  ;
DR   P30418, NMT_CANAL  ;  O74234, NMT_CANGA  ;  P0CP21, NMT_CRYNB  ;
DR   P34809, NMT_CRYNE  ;  P0CP20, NMT_CRYNJ  ;  Q6BJF4, NMT_DEBHA  ;
DR   Q553B6, NMT_DICDI  ;  O61613, NMT_DROME  ;  Q8TFN1, NMT_EMENI  ;
DR   Q75EK2, NMT_EREGS  ;  Q4I061, NMT_GIBZE  ;  Q6CMK4, NMT_KLULA  ;
DR   Q5UR64, NMT_MIMIV  ;  Q9YW20, NMT_MSEPV  ;  Q7S3C8, NMT_NEUCR  ;
DR   Q8ILW6, NMT_PLAF7  ;  Q9U419, NMT_PLAFA  ;  O43010, NMT_SCHPO  ;
DR   Q4PB56, NMT_USTMA  ;  Q6C7G2, NMT_YARLI  ;  P14743, NMT_YEAST  ;
//