ENZYME entry: EC 2.3.3.1

Accepted Name
Citrate (Si)-synthase.
Alternative Name(s)
(R)-citrate synthase.
Citrate oxaloacetate-lyase ((pro-3S)-CH(2)COO->acetyl-CoA).
Reaction catalysed
Acetyl-CoA + H(2)O + oxaloacetate <=> citrate + CoA
Comment(s)
  • The stereospecificity of this enzyme is opposite to that of EC 2.3.3.3, which is found in some anaerobes.
  • Formerly EC 4.1.3.7.
  • Citrate synthase for which the stereospecificity with respect to C(2) of oxaloacetate has not been established are included in EC 2.3.3.16.
Cross-references
PROSITEPDOC00422
BRENDA2.3.3.1
EC2PDB2.3.3.1
ExplorEnz2.3.3.1
PRIAM enzyme-specific profiles2.3.3.1
KEGG Ligand Database for Enzyme Nomenclature2.3.3.1
IUBMB Enzyme Nomenclature2.3.3.1
IntEnz2.3.3.1
MEDLINEFind literature relating to 2.3.3.1
MetaCyc2.3.3.1
UniProtKB/Swiss-Prot
Q17GM7, CISY1_AEDAE;  Q9LXS7, CISY1_ARATH;  P9WPD4, CISY1_MYCTO;  
P9WPD5, CISY1_MYCTU;  P51037, CISY1_RHITR;  P00890, CISY1_YEAST;  
Q16P20, CISY2_AEDAE;  Q9LXS6, CISY2_ARATH;  P39120, CISY2_BACSU;  
P63778, CISY2_MYCBO;  P9WPD2, CISY2_MYCTO;  P9WPD3, CISY2_MYCTU;  
P51038, CISY2_RHITR;  P08679, CISY2_YEAST;  Q9SJH7, CISY3_ARATH;  
P45858, CISY3_BACSU;  P43635, CISY3_YEAST;  P20115, CISY4_ARATH;  
Q9M1D3, CISY5_ARATH;  Q86AV6, CISYC_DICDI;  Q553V1, CISYM_DICDI;  
Q8MQU6, CISYP_DICDI;  O34002, CISY_ABDS2;  P20901, CISY_ACEAC;  
P20902, CISY_ACIAN;  P51045, CISY_ACIFR;  Q0GNE1, CISY_AMBCR;  
P51044, CISY_ASPNG;  Q59136, CISY_ASTRI;  P27660, CISY_BACCO;  
P39119, CISY_BACSU;  P51031, CISY_BARBA;  Q59198, CISY_BARDO;  
P51032, CISY_BAREL;  P51033, CISY_BARHE;  P51034, CISY_BARQU;  
Q59258, CISY_BARTA;  P51035, CISY_BARVB;  P51036, CISY_BARVI;  
Q29RK1, CISY_BOVIN;  P94325, CISY_BRADU;  Q61JF9, CISY_CAEBR;  
P34575, CISY_CAEEL;  P79024, CISY_CANTR;  P23007, CISY_CHICK;  
P49298, CISY_CITMA;  P42457, CISY_CORGL;  P18789, CISY_COXBU;  
Q7ZVY5, CISY_DANRE;  O80433, CISY_DAUCA;  Q9RWB2, CISY_DEIRA;  
Q9W401, CISY_DROME;  P0ABH8, CISY_ECOL6;  P0ABH7, CISY_ECOLI;  
O00098, CISY_EMENI;  P83372, CISY_FRAAN;  Q0QHL3, CISY_GLOMM;  
Q9ZN37, CISY_HELPJ;  P56062, CISY_HELPY;  O75390, CISY_HUMAN;  
Q0GNE0, CISY_IGUIG;  Q6S9V7, CISY_KATPE;  A4H9H8, CISY_LEIBR;  
A4HXU4, CISY_LEIIN;  Q4QDX3, CISY_LEIMA;  P0C1Z2, CISY_MACFA;  
Q0QEL7, CISY_MESAU;  Q9CZU6, CISY_MOUSE;  P26491, CISY_MYCSM;  
P34085, CISY_NEUCR;  P00889, CISY_PIG;  P84543, CISY_POPEU;  
P14165, CISY_PSEAE;  Q53554, CISY_PYRFU;  Q8VHF5, CISY_RAT;  
O33915, CISY_RHIME;  Q59732, CISY_RICAE;  Q59730, CISY_RICAK;  
P51039, CISY_RICAU;  Q59734, CISY_RICBE;  Q1RGV8, CISY_RICBR;  
P51041, CISY_RICCA;  P51042, CISY_RICCN;  P51040, CISY_RICFE;  
Q59741, CISY_RICHE;  Q59742, CISY_RICJA;  Q59748, CISY_RICMA;  
Q59759, CISY_RICPA;  P09948, CISY_RICPR;  Q59768, CISY_RICRH;  
Q59776, CISY_RICS1;  Q59778, CISY_RICSI;  P51043, CISY_RICTY;  
O68883, CISY_SALTY;  Q10306, CISY_SCHPO;  Q43175, CISY_SOLTU;  
P20903, CISY_STRHY;  Q59939, CISY_STRMU;  P80148, CISY_SULSO;  
Q59977, CISY_SYNY3;  Q6S9V5, CISY_TETAD;  Q4S5X1, CISY_TETNG;  
P24118, CISY_TETTH;  P21553, CISY_THEAC;  Q6S9V9, CISY_THUAL;  
Q6S9V8, CISY_THUOB;  Q7ZWZ5, CISY_XENLA;  Q28DK1, CISY_XENTR;  
Q6S9V6, CISY_XIPGL;  P49299, CYSZ_CUCMA;  

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