ID   2.3.3.10
DE   Hydroxymethylglutaryl-CoA synthase.
AN   (S)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-
AN   acetylating).
AN   3-hydroxy-3-methylglutaryl CoA synthetase.
AN   3-hydroxy-3-methylglutaryl coenzyme A synthase.
AN   3-hydroxy-3-methylglutaryl coenzyme A synthetase.
AN   3-hydroxy-3-methylglutaryl-CoA synthase.
AN   3-hydroxy-3-methylglutaryl-coenzyme A synthase.
AN   Acetoacetyl coenzyme A transacetase.
AN   Beta-hydroxy-beta-methylglutaryl-CoA synthase.
AN   HMG-CoA synthase.
AN   Hydroxymethylglutaryl coenzyme A synthase.
AN   Hydroxymethylglutaryl coenzyme alpha-condensing enzyme.
CA   Acetyl-CoA + H(2)O + acetoacetyl-CoA = (S)-3-hydroxy-3-methylglutaryl-CoA
CA   + CoA.
CC   -!- Formerly EC 4.1.3.5.
PR   PROSITE; PDOC00942;
DR   P54961, HMCS1_BLAGE;  P23228, HMCS1_CHICK;  P13704, HMCS1_CRIGR;
DR   Q01581, HMCS1_HUMAN;  Q8JZK9, HMCS1_MOUSE;  Q5R7Z9, HMCS1_PONAB;
DR   P17425, HMCS1_RAT  ;  P54870, HMCS2_BLAGE;  Q2KIE6, HMCS2_BOVIN;
DR   P54868, HMCS2_HUMAN;  P54869, HMCS2_MOUSE;  O02734, HMCS2_PIG  ;
DR   P22791, HMCS2_RAT  ;  P54872, HMCSA_DICDI;  Q86HL5, HMCSB_DICDI;
DR   P54873, HMCS_ARATH ;  P54871, HMCS_CAEEL ;  P54874, HMCS_SCHPO ;
DR   P54839, HMCS_YEAST ;
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