ENZYME entry: EC 2.4.1.101
| Accepted Name |
|---|
| Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase.
|
| Alternative Name(s) |
|---|
| Alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase. |
| GnTI. |
| N-acetylglucosaminyltransferase I. |
| N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase
I. |
| UDP-N-acetylglucosaminyl:alpha-1,3-D-mannoside-beta-1,2-N-
acetylglucosaminyltransferase I. |
| UDP-N-acetylglucosaminyl:alpha-3-D-mannoside beta-1,2-N-
acetylglucosaminyltransferase I. |
| Uridine diphosphoacetylglucosamine-alpha-1,3-mannosylglycoprotein beta-
1,2-N-acetylglucosaminyltransferase. |
| Reaction catalysed |
|---|
| UDP-N-acetyl-D-glucosamine + 3-(alpha-D-mannosyl)-beta-D-mannosyl-R <=> UDP + 3-(2-(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl)-beta-D-mannosyl-R |
| Comment(s) |
|---|
- R represents the remainder of the N-linked oligosaccharide in the
glycoprotein acceptor.
- Note that this enzyme acts before N-acetylglucosaminyltransferases II
(EC 2.4.1.143), III (EC 2.4.1.144), IV (EC 2.4.1.145),
V (EC 2.4.1.155) and VI (EC 2.4.1.201).
- Formerly EC 2.4.1.51.
|
| Cross-references |
|---|
| BRENDA | 2.4.1.101 |
| EC2PDB | 2.4.1.101 |
| ExplorEnz | 2.4.1.101 |
| PRIAM enzyme-specific profiles | 2.4.1.101 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.4.1.101 |
| IUBMB Enzyme Nomenclature | 2.4.1.101 |
| IntEnz | 2.4.1.101 |
| MEDLINE | Find literature relating to 2.4.1.101 |
| MetaCyc | 2.4.1.101 |
| UniProtKB/Swiss-Prot |
|
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