ENZYME entry: EC 2.4.1.152
| Accepted Name |
|---|
| 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase.
|
| Alternative Name(s) |
|---|
| Galactoside 3-fucosyltransferase. |
| GDP-L-fucose:1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-L-
fucosyltransferase. |
| Guanosine diphosphofucose-glucoside alpha-1->3-fucosyltransferase. |
| Lewis-negative alpha-3-fucosyltransferase. |
| Plasma alpha-3-fucosyltransferase. |
| Reaction catalysed |
|---|
| GDP-beta-L-fucose + (1->4)-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R <=> GDP + (1->4)-beta-D-galactosyl-(alpha-(1->3)-L-fucosyl)-N-acetyl-D-glucosaminyl-R |
| Comment(s) |
|---|
- Normally acts on a glycoconjugate where R (see CA line) is a
glycoprotein or glycolipid.
- This enzyme fucosylates on O-3 of an N-acetylglucosamine that carries
a galactosyl group on O-4, unlike EC 2.4.1.65, which fucosylates on
O-4 of an N-acetylglucosamine that carries a galactosyl group on O-3.
|
| Cross-references |
|---|
| BRENDA | 2.4.1.152 |
| EC2PDB | 2.4.1.152 |
| ExplorEnz | 2.4.1.152 |
| PRIAM enzyme-specific profiles | 2.4.1.152 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.4.1.152 |
| IUBMB Enzyme Nomenclature | 2.4.1.152 |
| IntEnz | 2.4.1.152 |
| MEDLINE | Find literature relating to 2.4.1.152 |
| MetaCyc | 2.4.1.152 |
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