ENZYME entry: EC 2.4.1.165

Accepted Name
N-acetylneuraminylgalactosylglucosylceramide beta-1,4-N- acetylgalactosaminyltransferase.
Reaction catalysed
UDP-N-acetyl-alpha-D-galactosamine + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide <=> UDP + N-acetyl-beta-D-galactosaminyl-(1->4)-(alpha-N-acetylneuraminyl-(2->3))-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide
Cofactor(s)
Mn(2+).
Comment(s)
Only substances containing sialic acid residues can act as acceptors; bovine fetuin is the best acceptor tested.
Cross-references
BRENDA2.4.1.165
EC2PDB2.4.1.165
ExplorEnz2.4.1.165
PRIAM enzyme-specific profiles2.4.1.165
KEGG Ligand Database for Enzyme Nomenclature2.4.1.165
IUBMB Enzyme Nomenclature2.4.1.165
IntEnz2.4.1.165
MEDLINEFind literature relating to 2.4.1.165
MetaCyc2.4.1.165

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