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ENZYME entry: EC 2.4.1.182

Accepted Name
Lipid-A-disaccharide synthase.
Reaction catalysed
UDP-2-N,3-O-bis((3R)-3-hydroxytetradecanoyl)-alpha-D-glucosamine + 2-N,3-O-bis((3R)-3-hydroxytetradecanoyl)-alpha-D-glucosaminyl 1-phosphate <=> UDP + 2-N,3-O-bis((3R)-3-hydroxytetradecanoyl)-beta-D-glucosaminyl-(1->6)-2-N,3-O-bis((3R)-3-hydroxytetradecanoyl)-alpha-D-glucosaminyl 1-phosphate
Comment(s)
Involved with EC 2.3.1.129 and EC 2.7.1.130 in the biosynthesis of the phosphorylated glycolipid, lipid A, in the outer membrane of Escherichia coli.
Cross-references
BRENDA2.4.1.182
EC2PDB2.4.1.182
ExplorEnz2.4.1.182
PRIAM enzyme-specific profiles2.4.1.182
KEGG Ligand Database for Enzyme Nomenclature2.4.1.182
IUBMB Enzyme Nomenclature2.4.1.182
IntEnz2.4.1.182
MEDLINEFind literature relating to 2.4.1.182
MetaCyc2.4.1.182
UniProtKB/Swiss-Prot
Q5X5J5, LPXB1_LEGPA;  Q5ZVR9, LPXB1_LEGPH;  Q5WWX7, LPXB1_LEGPL;  
Q5X0T2, LPXB2_LEGPA;  Q5ZRD7, LPXB2_LEGPH;  Q5WSK6, LPXB2_LEGPL;  
Q6FA07, LPXB_ACIAD;  C1F718, LPXB_ACIC5;  A3MY79, LPXB_ACTP2;  
B3GZJ7, LPXB_ACTP7;  B0BRG6, LPXB_ACTPJ;  A0KHH6, LPXB_AERHH;  
Q0VQE4, LPXB_ALCBS;  B6EJW7, LPXB_ALISL;  Q0A7J2, LPXB_ALKEH;  
B4RVJ5, LPXB_ALTMD;  B8JE78, LPXB_ANAD2;  Q2IL69, LPXB_ANADE;  
B4UHR6, LPXB_ANASK;  O67420, LPXB_AQUAE;  F4IF99, LPXB_ARATH;  
Q5NZG2, LPXB_AROAE;  A1K6Q8, LPXB_AZOSB;  C1DST3, LPXB_AZOVD;  
Q7VRD3, LPXB_BLOFL;  Q493B9, LPXB_BLOPB;  Q2L147, LPXB_BORA1;  
Q7WJ81, LPXB_BORBR;  Q7WA47, LPXB_BORPA;  A9INR9, LPXB_BORPD;  
Q7VYB7, LPXB_BORPE;  Q89KQ7, LPXB_BRADU;  B1YS61, LPXB_BURA4;  
Q1BHG9, LPXB_BURCA;  B1JUD7, LPXB_BURCC;  A0K8D0, LPXB_BURCH;  
B4ECL8, LPXB_BURCJ;  Q0BE28, LPXB_BURCM;  Q39F56, LPXB_BURL3;  
A9AIM7, LPXB_BURM1;  A3MKS9, LPXB_BURM7;  A2SB86, LPXB_BURM9;  
Q62JD7, LPXB_BURMA;  A1V555, LPXB_BURMS;  A3NWL7, LPXB_BURP0;  
Q3JR42, LPXB_BURP1;  A3NAT4, LPXB_BURP6;  Q63T25, LPXB_BURPS;  
Q2SWY5, LPXB_BURTA;  A4JF62, LPXB_BURVG;  A8FK76, LPXB_CAMJ8;  
Q9PIK8, LPXB_CAMJE;  Q5HWH9, LPXB_CAMJR;  B3PBR1, LPXB_CELJU;  
Q5L586, LPXB_CHLAB;  Q821Z3, LPXB_CHLCV;  Q255P5, LPXB_CHLFF;  
Q9PJY4, LPXB_CHLMU;  Q9Z6U3, LPXB_CHLPN;  Q3KLU2, LPXB_CHLTA;  
O84416, LPXB_CHLTR;  Q1R020, LPXB_CHRSD;  Q7NVY1, LPXB_CHRVO;  
A8ALA6, LPXB_CITK8;  Q485F5, LPXB_COLP3;  B6J9H1, LPXB_COXB1;  
B6J161, LPXB_COXB2;  A9KC41, LPXB_COXBN;  A9NCA7, LPXB_COXBR;  
Q83DS5, LPXB_COXBU;  Q1LNE5, LPXB_CUPMC;  Q470F0, LPXB_CUPNJ;  
B7KFS1, LPXB_CYAP7;  Q47F79, LPXB_DECAR;  Q6ALW0, LPXB_DESPS;  
A7ZHS2, LPXB_ECO24;  B7UJ83, LPXB_ECO27;  B7MBG3, LPXB_ECO45;  
B7LGP4, LPXB_ECO55;  Q8X8X7, LPXB_ECO57;  B5Z0G1, LPXB_ECO5E;  
B7NIE4, LPXB_ECO7I;  B7MP42, LPXB_ECO81;  B7M1Y5, LPXB_ECO8A;  
C4ZRS4, LPXB_ECOBW;  B1XD51, LPXB_ECODH;  A7ZWC8, LPXB_ECOHS;  
A1A7M6, LPXB_ECOK1;  Q0TLF1, LPXB_ECOL5;  Q8FL07, LPXB_ECOL6;  
B1IQF9, LPXB_ECOLC;  P10441, LPXB_ECOLI;  B7N849, LPXB_ECOLU;  
B6HZF6, LPXB_ECOSE;  B1LGY4, LPXB_ECOSM;  Q1RG07, LPXB_ECOUT;  
A4W6S7, LPXB_ENT38;  B2VHX9, LPXB_ERWT9;  B7LW61, LPXB_ESCF3;  
B0TXG8, LPXB_FRAP2;  Q14G55, LPXB_FRAT1;  A7NAP6, LPXB_FRATF;  
Q2A4P3, LPXB_FRATH;  B2SFX3, LPXB_FRATM;  A0Q7X9, LPXB_FRATN;  
Q0BN19, LPXB_FRATO;  Q5NEQ2, LPXB_FRATT;  A4IWJ7, LPXB_FRATW;  
B3E4H8, LPXB_GEOLS;  Q39T49, LPXB_GEOMG;  Q74AT9, LPXB_GEOSL;  
Q5FUA3, LPXB_GLUOX;  Q0BS63, LPXB_GRABC;  Q7VMW5, LPXB_HAEDU;  
Q4QLM6, LPXB_HAEI8;  A5UD44, LPXB_HAEIE;  A5UII8, LPXB_HAEIG;  
P45011, LPXB_HAEIN;  B8F5I8, LPXB_HAEPS;  Q0I4M5, LPXB_HAES1;  
Q2SBR1, LPXB_HAHCH;  Q17WJ2, LPXB_HELAH;  B6JM91, LPXB_HELP2;  
B5Z7M7, LPXB_HELPG;  Q1CT05, LPXB_HELPH;  Q9ZKY2, LPXB_HELPJ;  
B2USW3, LPXB_HELPS;  O25537, LPXB_HELPY;  B0UW62, LPXB_HISS2;  
Q31G55, LPXB_HYDCU;  Q5QYW1, LPXB_IDILO;  B5Y1I9, LPXB_KLEP3;  
A6T4Y4, LPXB_KLEP7;  Q1INL4, LPXB_KORVE;  A0L8R9, LPXB_MAGMM;  
Q2W4D7, LPXB_MAGSA;  Q65VI1, LPXB_MANSM;  Q1H152, LPXB_METFK;  
Q1D393, LPXB_MYXXD;  Q5F5Y6, LPXB_NEIG1;  Q9JX45, LPXB_NEIMA;  
Q9K1F5, LPXB_NEIMB;  A1KRN0, LPXB_NEIMF;  Q1QMM4, LPXB_NITHX;  
Q3JAC1, LPXB_NITOC;  Q3SRI5, LPXB_NITWN;  B2JIB3, LPXB_PARP8;  
B2T5I1, LPXB_PARPJ;  Q13XC9, LPXB_PARXL;  Q9CJK7, LPXB_PASMU;  
Q6D8D0, LPXB_PECAS;  C6DAJ6, LPXB_PECCP;  Q3A550, LPXB_PELCD;  
C0QR27, LPXB_PERMH;  Q7N8N4, LPXB_PHOLL;  Q6LN37, LPXB_PHOPR;  
A2C745, LPXB_PROM3;  P72216, LPXB_PROMI;  Q7V5X6, LPXB_PROMM;  
Q48F72, LPXB_PSE14;  A6V1E5, LPXB_PSEA7;  B7V7U5, LPXB_PSEA8;  
Q02RB5, LPXB_PSEAB;  Q9HXY8, LPXB_PSEAE;  Q1I639, LPXB_PSEE4;  
Q4KHG3, LPXB_PSEF5;  C3K6G9, LPXB_PSEFS;  Q3IIW8, LPXB_PSEHT;  
A4XWS8, LPXB_PSEMY;  A5W837, LPXB_PSEP1;  Q3KH99, LPXB_PSEPF;  
B0KSB2, LPXB_PSEPG;  Q88MG7, LPXB_PSEPK;  B1JBP7, LPXB_PSEPW;  
Q886N0, LPXB_PSESM;  Q4ZWR5, LPXB_PSEU2;  A1SYV0, LPXB_PSYIN;  
Q8XZH8, LPXB_RALSO;  B6IST7, LPXB_RHOCS;  Q21WX7, LPXB_RHOFT;  
Q2IW93, LPXB_RHOP2;  Q6N5R2, LPXB_RHOPA;  Q215D6, LPXB_RHOPB;  
A8GN02, LPXB_RICAH;  A8GU85, LPXB_RICB8;  Q1RIC1, LPXB_RICBR;  
A8EZC6, LPXB_RICCK;  Q92II0, LPXB_RICCN;  Q4UJN0, LPXB_RICFE;  
Q9ZDK7, LPXB_RICPR;  Q68X51, LPXB_RICTY;  Q5LSU1, LPXB_RUEPO;  
Q21HI5, LPXB_SACD2;  B5F8U3, LPXB_SALA4;  A9MPH9, LPXB_SALAR;  
Q57T26, LPXB_SALCH;  B5FJ29, LPXB_SALDC;  B5R421, LPXB_SALEP;  
B5RHG7, LPXB_SALG2;  B4TK57, LPXB_SALHS;  B4SV11, LPXB_SALNS;  
Q5PD72, LPXB_SALPA;  A9N0T2, LPXB_SALPB;  C0Q6K5, LPXB_SALPC;  
B5BAN9, LPXB_SALPK;  B4TYE2, LPXB_SALSV;  Q8Z9A1, LPXB_SALTI;  
Q8ZRN9, LPXB_SALTY;  A8GID3, LPXB_SERP5;  A1S4Q3, LPXB_SHEAM;  
B8E7Q3, LPXB_SHEB2;  Q085C9, LPXB_SHEFN;  B0TP70, LPXB_SHEHH;  
A3QG90, LPXB_SHELP;  Q8EGG2, LPXB_SHEON;  A8H6K3, LPXB_SHEPA;  
A4Y556, LPXB_SHEPC;  A0KZ10, LPXB_SHESA;  A8FY29, LPXB_SHESH;  
Q0HGW8, LPXB_SHESM;  Q0HT75, LPXB_SHESR;  A1RLL4, LPXB_SHESW;  
B1KNT0, LPXB_SHEWM;  B2U325, LPXB_SHIB3;  Q325V8, LPXB_SHIBS;  
Q32JS7, LPXB_SHIDS;  Q0T827, LPXB_SHIF8;  Q83SL3, LPXB_SHIFL;  
Q3Z5H6, LPXB_SHISS;  Q2NRM0, LPXB_SODGM;  Q02AZ6, LPXB_SOLUE;  
B2V704, LPXB_SULSY;  Q2LVL8, LPXB_SYNAS;  Q57310, LPXB_SYNY3;  
Q3SKM8, LPXB_THIDA;  A1WHV5, LPXB_VEREI;  A5F627, LPXB_VIBC3;  
A7MY02, LPXB_VIBCB;  Q9KPW5, LPXB_VIBCH;  C3LQ19, LPXB_VIBCM;  
Q5E3F2, LPXB_VIBF1;  B5F9W3, LPXB_VIBFM;  Q87MF0, LPXB_VIBPA;  
Q8DBE8, LPXB_VIBVU;  Q7MIH2, LPXB_VIBVY;  Q8D2H4, LPXB_WIGBR;  
Q8PML8, LPXB_XANAC;  Q3BVL7, LPXB_XANC5;  Q4USP7, LPXB_XANC8;  
Q8PAW6, LPXB_XANCP;  Q2P4B8, LPXB_XANOM;  Q5H1F3, LPXB_XANOR;  
B2I7N8, LPXB_XYLF2;  Q9PEI6, LPXB_XYLFA;  B0U236, LPXB_XYLFM;  
Q87EI5, LPXB_XYLFT;  Q8ZH55, LPXB_YERPE;  Q667K2, LPXB_YERPS;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-