ENZYME entry: EC 2.4.1.217
| Accepted Name |
|---|
| Mannosyl-3-phosphoglycerate synthase.
|
| Alternative Name(s) |
|---|
| MPG synthase. |
| Reaction catalysed |
|---|
| GDP-mannose + 3-phospho-D-glycerate <=> GDP + 2-(alpha-D-mannosyl)-3-phosphoglycerate |
| Cofactor(s) |
|---|
| Magnesium.
|
| Comment(s) |
|---|
- The enzyme is absolutely specific for GDP-mannose and
3-phosphoglycerate, and transfers the mannosyl group with retention
of configuration.
- In the hyperthermophilic archaeon Pyrococcus horikoshii,
the mannosyl-3-phosphoglycerate formed is subsequently
dephosphorylated by a specific phosphatase, EC 3.1.3.70, producing
mannosylglycerate.
|
| Cross-references |
|---|
| BRENDA | 2.4.1.217 |
| EC2PDB | 2.4.1.217 |
| ExplorEnz | 2.4.1.217 |
| PRIAM enzyme-specific profiles | 2.4.1.217 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.4.1.217 |
| IUBMB Enzyme Nomenclature | 2.4.1.217 |
| IntEnz | 2.4.1.217 |
| MEDLINE | Find literature relating to 2.4.1.217 |
| MetaCyc | 2.4.1.217 |
| UniProtKB/Swiss-Prot |
|
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