ID   2.4.1.226
DE   N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase.
AN   Chondroitin glucuronyltransferase II.
CA   UDP-alpha-D-glucuronate + N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-
CA   glucuronosyl-proteoglycan = UDP + beta-D-glucuronosyl-(1->3)-N-acetyl-
CA   beta-D-galactosaminyl-(1->4)-beta-D-glucuronosyl-proteoglycan.
CC   -!- Involved in the biosynthesis of chondroitin and dermatan sulfate.
CC   -!- The human chondroitin synthetase is a bifunctional
CC       glycosyltransferase, which also has the EC 2.4.1.175 activity
CC       required for the synthesis of the chondroitin sulfate disaccharide
CC       repeats.
CC   -!- Similar chondroitin synthase 'copolymerases' can be found in
CC       Pasteurella multocida and Escherichia coli.
CC   -!- There is also another human protein with apparently only the 3-beta-
CC       glucuronosyltransferase activity.
DR   Q9P2E5, CHPF2_HUMAN;  Q86X52, CHSS1_HUMAN;  Q6ZQ11, CHSS1_MOUSE;
DR   P45895, CHSS2_CAEEL;  Q8IZ52, CHSS2_HUMAN;  Q6IQX7, CHSS2_MOUSE;
DR   Q70JA7, CHSS3_HUMAN;  Q5DTK1, CHSS3_MOUSE;  Q8L0V4, CHS_ECOLX  ;
DR   Q9CMP0, CHS_PASMU  ;  Q7BLV3, HAS_PASMD  ;
//