ID 2.4.1.229 DE [Skp1-protein]-hydroxyproline N-acetylglucosaminyltransferase. AN Skp1-HyPro GlcNAc-transferase. AN UDP-N-acetylglucosamine (GlcNAc):hydroxyproline polypeptide GlcNAc- AN transferase. CA trans-4-hydroxy-L-prolyl-[Skp1 protein] + UDP-N-acetyl-alpha-D- CA glucosamine = H(+) + O-(N-acetyl-alpha-D-glucosaminyl)-trans-4-hydroxy-L- CA prolyl-[Skp1 protein] + UDP. CC -!- Skp1 is a cytoplasmic and nuclear protein required for the CC ubiquitination of cell cycle regulatory proteins and transcriptional CC factors. CC -!- In Dictyostelium Skp1 is modified by the linear pentasaccharide CC Galalpha1-6Galalpha1-L-Fucalpha1-2Galbeta1-3GlcNAc, which is attached CC to a hydroxyproline residue at position 143. CC -!- This enzyme catalyzes the first step in the building up of the CC pentasaccharide by attaching an N-acetylglucosaminyl group to the CC hydroxyproline residue. DR Q8T1C6, GNT1_DICDI ; //