Expasy logo

ENZYME

ENZYME entry: EC 2.4.1.246

Accepted Name
mannosylfructose-phosphate synthase
Alternative Name(s)
mannosylfructose-6-phosphate synthase
MFPS
Reaction catalysed
beta-D-fructose 6-phosphate + GDP-alpha-D-mannose <=> beta-D-fructofuranosyl alpha-D-mannopyranoside 6(F)-phosphate + GDP + H(+)
Comment(s)
  • GDP-mannose can be replaced by ADP-mannose but with a concomitant decrease in activity.
  • The product of this reaction is dephosphorylated by EC 3.1.3.79 to form the non-reducing disaccharide mannosylfructose, which is the major endogenous osmolyte produced by several alpha-proteobacteria in response to osmotic stress.
  • The F in the product name is used to indicate that the fructose residue of sucrose carries the substituent.
Cross-references
BRENDA2.4.1.246
EC2PDB2.4.1.246
ExplorEnz2.4.1.246
PRIAM enzyme-specific profiles2.4.1.246
KEGG Ligand Database for Enzyme Nomenclature2.4.1.246
IUBMB Enzyme Nomenclature2.4.1.246
IntEnz2.4.1.246
MEDLINEFind literature relating to 2.4.1.246
MetaCyc2.4.1.246
Rhea expert-curated reactions2.4.1.246
UniProtKB/Swiss-Prot
A7TZT2, MFPS_AGRFC

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-