To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https

ENZYME entry: EC 2.4.1.250

Accepted Name
D-inositol-3-phosphate glycosyltransferase.
Alternative Name(s)
Mycothiol glycosyltransferase.
N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase.
Reaction catalysed
UDP-N-acetyl-D-glucosamine + 1D-myo-inositol 3-phosphate <=> UDP + 1-O-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol 3-phosphate
Comment(s)
  • The enzyme, which belongs to the GT-B fold superfamily, catalyzes the first dedicated reaction in the biosynthesis of mycothiol.
  • The substrate was initially believed to be inositol, but eventually shown to be D-myo-inositol 3-phosphate.
  • A substantial conformational change occurs upon UDP binding, which generates the binding site for D-myo-inositol 3-phosphate.
  • Formerly EC 2.4.1.n3.
Cross-references
BRENDA2.4.1.250
EC2PDB2.4.1.250
ExplorEnz2.4.1.250
PRIAM enzyme-specific profiles2.4.1.250
KEGG Ligand Database for Enzyme Nomenclature2.4.1.250
IUBMB Enzyme Nomenclature2.4.1.250
IntEnz2.4.1.250
MEDLINEFind literature relating to 2.4.1.250
MetaCyc2.4.1.250
UniProtKB/Swiss-Prot
C7Q4Y6, MSHA1_CATAD;  C7QKE8, MSHA2_CATAD;  A0LQY9, MSHA_ACIC1;  
C6WPK3, MSHA_ACTMD;  A0JZ09, MSHA_ARTS2;  D5UJ42, MSHA_CELFN;  
C3PK12, MSHA_CORA7;  Q6NJL3, MSHA_CORDI;  Q8FSH1, MSHA_COREF;  
A4QB40, MSHA_CORGB;  Q8NTA6, MSHA_CORGL;  Q4JSW2, MSHA_CORJK;  
C4LLD6, MSHA_CORK4;  B1VEI4, MSHA_CORU7;  Q0RS49, MSHA_FRAAA;  
Q2JFV0, MSHA_FRACC;  A8LDJ8, MSHA_FRASN;  D2S4K7, MSHA_GEOOG;  
D0L476, MSHA_GORB4;  C7R101, MSHA_JONDD;  A6W6D9, MSHA_KINRD;  
D2Q1C4, MSHA_KRIFD;  A0QLK5, MSHA_MYCA1;  B1MHQ0, MSHA_MYCA9;  
P64708, MSHA_MYCBO;  A1KFW0, MSHA_MYCBP;  C1AKG4, MSHA_MYCBT;  
A4T324, MSHA_MYCGI;  B8ZT88, MSHA_MYCLB;  P54138, MSHA_MYCLE;  
B2HQV2, MSHA_MYCMM;  Q73SU4, MSHA_MYCPA;  A0QQZ8, MSHA_MYCS2;  
A3PU84, MSHA_MYCSJ;  A1UAM8, MSHA_MYCSK;  Q1BEA6, MSHA_MYCSS;  
A5TZL4, MSHA_MYCTA;  A5WJJ8, MSHA_MYCTF;  C6DT68, MSHA_MYCTK;  
P9WMY6, MSHA_MYCTO;  P9WMY7, MSHA_MYCTU;  A0PVZ1, MSHA_MYCUA;  
A1T3B5, MSHA_MYCVP;  C8XA09, MSHA_NAKMY;  D7AW65, MSHA_NOCDD;  
Q5YP47, MSHA_NOCFA;  A1SP12, MSHA_NOCSJ;  A1R8N8, MSHA_PAEAT;  
B8HCF8, MSHA_PSECP;  C0ZUT0, MSHA_RHOE4;  Q0SF06, MSHA_RHOJR;  
C1AZ64, MSHA_RHOOB;  A4FQ08, MSHA_SACEN;  C7MSY6, MSHA_SACVD;  
A8LZG1, MSHA_SALAI;  A4X1R6, MSHA_SALTO;  D1BD84, MSHA_SANKS;  
D6Z995, MSHA_SEGRD;  D3Q051, MSHA_STANL;  Q82G92, MSHA_STRAW;  
D7C367, MSHA_STRBB;  Q9FCG5, MSHA_STRCO;  B1VS68, MSHA_STRGG;  
D2B9F4, MSHA_STRRD;  C9ZH13, MSHA_STRSW;  D6Y4U7, MSHA_THEBD;  
D1A4Q3, MSHA_THECD;  Q47KS6, MSHA_THEFY;  D5USX8, MSHA_TSUPD;  
D1BZ82, MSHA_XYLCX;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-