To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https

ENZYME entry: EC 2.4.1.256

Accepted Name
Dolichyl-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-dolichol alpha-1,2- glucosyltransferase.
Alternative Name(s)
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase.
Reaction catalysed
Dolichyl beta-D-glucosyl phosphate + D-Glc-alpha-(1->3)-D-Glc-alpha-(1->3)-D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-[D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-(D-Man-alpha-(1->2)-D-Man-alpha-(1->6))-D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol <=> D-Glc-alpha-(1->2)-D-Glc-alpha-(1->3)-D-Glc-alpha-(1->3)-D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-[D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-(D-Man-alpha-(1->2)-D-Man-alpha-(1->6))-D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate
Comment(s)
  • This eukaryotic enzyme performs the final step in the synthesis of the lipid-linked oligosaccharide, attaching D-glucose in an alpha- 1,2-linkage to the outermost D-glucose in the long branch.
  • The lipid-linked oligosaccharide is involved in N-linked protein glycosylation of selected asparagine residues of nascent polypeptide chains in eukaryotic cells.
Cross-references
BRENDA2.4.1.256
EC2PDB2.4.1.256
ExplorEnz2.4.1.256
PRIAM enzyme-specific profiles2.4.1.256
KEGG Ligand Database for Enzyme Nomenclature2.4.1.256
IUBMB Enzyme Nomenclature2.4.1.256
IntEnz2.4.1.256
MEDLINEFind literature relating to 2.4.1.256
MetaCyc2.4.1.256
UniProtKB/Swiss-Prot
Q5BKT4, AG10A_HUMAN;  Q5I7T1, AG10B_HUMAN;  Q3UGP8, AG10B_MOUSE;  
O88788, AG10B_RAT;  Q8L638, ALG10_ARATH;  Q75AQ8, ALG10_ASHGO;  
Q4X162, ALG10_ASPFU;  Q59YV2, ALG10_CANAL;  Q6FL34, ALG10_CANGA;  
Q6BW42, ALG10_DEBHA;  Q8T8L8, ALG10_DROME;  Q5B0M8, ALG10_EMENI;  
Q4HZE0, ALG10_GIBZE;  Q6CN27, ALG10_KLULA;  P0C147, ALG10_MAGO7;  
Q7SA35, ALG10_NEUCR;  Q10254, ALG10_SCHPO;  Q4P2W6, ALG10_USTMA;  
Q6CEA5, ALG10_YARLI;  P50076, ALG10_YEAST;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-