ID   2.4.1.257
DE   GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase.
AN   GDP-Man:Man2GlcNAc2-PP-Dol alpha-1,6-mannosyltransferase.
CA   alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-
CA   diphosphodolichol + GDP-alpha-D-mannose = alpha-D-Man-(1->3)-[alpha-D-
CA   Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-
CA   diphosphodolichol + GDP + H(+).
CC   -!- The biosynthesis of asparagine-linked glycoproteins utilizes a
CC       dolichyl diphosphate-linked glycosyl donor, which is assembled by the
CC       series of membrane-bound glycosyltransferases that comprise the
CC       dolichol pathway.
CC   -!- Alg2 mannosyltransferase from Saccharomyces cerevisiae carries out an
CC       alpha1,3-mannosylation (cf. EC 2.4.1.132) of D-Man-beta-(1->4)-D-
CC       GlcNAc-beta-(1->4)-GlcNAc-diphosphodolichol, followed by an alpha1,6-
CC       mannosylation, to form the first branched pentasaccharide
CC       intermediate of the dolichol pathway.
DR   Q59LF2, ALG2_CANAL ;  Q6FJJ9, ALG2_CANGA ;  Q6BVA4, ALG2_DEBHA ;
DR   Q7KWM5, ALG2_DICDI ;  Q755C1, ALG2_EREGS ;  Q9H553, ALG2_HUMAN ;
DR   Q6CWQ0, ALG2_KLULA ;  Q9DBE8, ALG2_MOUSE ;  Q8X0H8, ALG2_NEUCR ;
DR   O94738, ALG2_RHIPU ;  Q96WW6, ALG2_SCHPO ;  Q6C3V7, ALG2_YARLI ;
DR   P43636, ALG2_YEAST ;
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