ENZYME entry: EC 2.4.1.287

Accepted Name
Rhamnopyranosyl-N-acetylglucosaminyl-diphospho-decaprenol beta-1,3/1,4- galactofuranosyltransferase.
Alternative Name(s)
Arabinogalactan galactofuranosyl transferase 1.
Reaction catalysed
2 UDP-alpha-D-galactofuranose + alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol <=> 2 UDP + beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
Comment(s)
  • Isolated from Mycobacterium tuberculosis and M.smegmatis, the enzyme has dual beta-(1->4) and beta-(1->5) transferase action.
  • Involved in the formation of the cell wall in mycobacteria.
Cross-references
BRENDA2.4.1.287
EC2PDB2.4.1.287
ExplorEnz2.4.1.287
PRIAM enzyme-specific profiles2.4.1.287
KEGG Ligand Database for Enzyme Nomenclature2.4.1.287
IUBMB Enzyme Nomenclature2.4.1.287
IntEnz2.4.1.287
MEDLINEFind literature relating to 2.4.1.287
MetaCyc2.4.1.287
UniProtKB/Swiss-Prot
A0R5Z2, GLFT1_MYCS2;  P9WMX2, GLFT1_MYCTO;  P9WMX3, GLFT1_MYCTU;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.1.-
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