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ENZYME entry: EC 2.4.1.289

Accepted Name
N-acetylglucosaminyl-diphospho-decaprenol L-rhamnosyltransferase.
Reaction catalysed
dTDP-6-deoxy-beta-L-mannose + N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol <=> dTDP + alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
Cofactor(s)
Mn(2+) or Mg(2+).
Comment(s)
  • Isolated from Mycobacterium smegmatis and Mycobacterium tuberculosis.
  • The enzyme catalyzes the addition of a rhamnosyl unit to N-acetyl- alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol, completing the synthesis of the linkage unit that attaches the arabinogalactan moiety to the peptidoglycan moiety in Mycobacterial cell wall.
Cross-references
BRENDA2.4.1.289
EC2PDB2.4.1.289
ExplorEnz2.4.1.289
PRIAM enzyme-specific profiles2.4.1.289
KEGG Ligand Database for Enzyme Nomenclature2.4.1.289
IUBMB Enzyme Nomenclature2.4.1.289
IntEnz2.4.1.289
MEDLINEFind literature relating to 2.4.1.289
MetaCyc2.4.1.289
UniProtKB/Swiss-Prot
P9WMY2, WBBL_MYCTO;  P9WMY3, WBBL_MYCTU;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.1.-
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