ENZYME entry: EC 2.4.1.315

Accepted Name
Diglucosyl diacylglycerol synthase (1,6-linking).
Alternative Name(s)
DGlcDAG synthase.
MGlcDAG (1->6) glucosyltransferase.
Monoglucosyl diacylglycerol (1->6) glucosyltransferase.
Reaction catalysed
  • UDP-alpha-D-glucose + 1,2-diacyl-3-O-(beta-D-glucopyranosyl)-sn-glycerol <=> 1,2-diacyl-3-O-(beta-D-glucopyranosyl-(1->6)-O-beta-D-glucopyranosyl)-sn-glycerol + UDP
  • UDP-alpha-D-glucose + 1,2-diacyl-3-O-(beta-D-glucopyranosyl-(1->6)-O-beta-D-glucopyranosyl)-sn-glycerol <=> 1,2-diacyl-3-O-(beta-D-glucopyranosyl-(1->6)-beta-D-glucopyranosyl-(1->6)-O-beta-D-glucopyranosyl)-sn-glycerol + UDP
Comment(s)
  • The enzyme is found in several bacterial species.
  • The enzyme from Bacillus subtilis is specific for glucose.
  • The enzyme from Mycoplasma genitalium can incoporate galactose with similar efficiency, but forms mainly 1,2-diacyl-diglucopyranosyl- sn-glycerol in vivo.
  • The enzyme from Staphylococcus aureus can also form glucosyl-glycero- 3-phospho-(1'-sn-glycerol).
Cross-references
BRENDA2.4.1.315
EC2PDB2.4.1.315
ExplorEnz2.4.1.315
PRIAM enzyme-specific profiles2.4.1.315
KEGG Ligand Database for Enzyme Nomenclature2.4.1.315
IUBMB Enzyme Nomenclature2.4.1.315
IntEnz2.4.1.315
MEDLINEFind literature relating to 2.4.1.315
MetaCyc2.4.1.315
UniProtKB/Swiss-Prot
C3PCX2, UGTP_BACAA;  C3LHC1, UGTP_BACAC;  A0R9F0, UGTP_BACAH;  
Q81YW9, UGTP_BACAN;  B7JNE4, UGTP_BACC0;  Q73DZ5, UGTP_BACC1;  
B7IW03, UGTP_BACC2;  C1EWE6, UGTP_BACC3;  B7H9Q4, UGTP_BACC4;  
B7HU46, UGTP_BACC7;  A7GKY0, UGTP_BACCN;  B9J2U2, UGTP_BACCQ;  
Q81IA1, UGTP_BACCR;  Q63GD0, UGTP_BACCZ;  Q6HNU4, UGTP_BACHK;  
Q65IA4, UGTP_BACLD;  A8FED1, UGTP_BACP2;  P54166, UGTP_BACSU;  
A9VSQ8, UGTP_BACWK;  A7X0P5, UGTP_STAA1;  A6U0C2, UGTP_STAA2;  
Q2FI60, UGTP_STAA3;  Q2FZP7, UGTP_STAA8;  A5IRJ3, UGTP_STAA9;  
Q2YWW6, UGTP_STAAB;  Q5HH69, UGTP_STAAC;  A6QFM7, UGTP_STAAE;  
Q99V75, UGTP_STAAM;  Q7A6D2, UGTP_STAAN;  Q6GI67, UGTP_STAAR;  
Q6GAR0, UGTP_STAAS;  A8Z0C1, UGTP_STAAT;  Q8NXC3, UGTP_STAAW;  
B9DQ98, UGTP_STACT;  Q5HQE7, UGTP_STAEQ;  Q8CPR3, UGTP_STAES;  
Q4L524, UGTP_STAHJ;  Q49WE6, UGTP_STAS1;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-