ID   2.4.1.47
DE   N-acylsphingosine galactosyltransferase.
AN   2-hydroxyacylsphingosine 1-beta-galactosyltransferase.
CA   an N-acylsphing-4-enine + UDP-alpha-D-galactose = a beta-D-galactosyl-
CA   (1<->1')-N-acylsphing-4-enine + H(+) + UDP.
CC   -!- This membrane-bound, endoplasmic reticulum-located enzyme catalyzes
CC       the last step in the synthesis of galactocerebrosides, which are
CC       abundant sphingolipids of the myelin membrane of the central nervous
CC       system and peripheral nervous system.
CC   -!- It has a strong preference for ceramides that contain hydroxylated
CC       fatty acids.
CC   -!- Formerly EC 2.4.1.45.
DR   Q16880, CGT_HUMAN  ;  Q64676, CGT_MOUSE  ;  Q09426, CGT_RAT    ;
//