To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https

ENZYME entry: EC

Accepted Name
Type 1 galactoside alpha-(1,2)-fucosyltransferase.
Alternative Name(s)
Beta-galactoside alpha-1->2 fucosyltransferase.
Blood group H alpha-2-fucosyltransferase.
Blood-group substance H-dependent fucosyltransferase.
Galactoside 2-alpha-L-fucosyltransferase.
Guanosine diphosphofucose-beta-D-galactosyl-alpha-2-L-fucosyltransferase.
Guanosine diphosphofucose-galactoside 2-L-fucosyltransferase.
Guanosine diphosphofucose- galactosylacetylglucosaminylgalactosylglucosylceramide alpha-L- fucosyltransferase.
Guanosine diphosphofucose-glycoprotein 2-alpha-fucosyltransferase.
Guanosine diphosphofucose-glycoprotein 2-alpha-L-fucosyltransferase.
Secretor-type beta-galactoside alpha-1->2 fucosyltransferase.
Reaction catalysed
GDP-beta-L-fucose + beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-R <=> GDP + alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-R
  • The enzyme acts on a glycoconjugates where the substituent group is a glycoprotein or glycosphingolipid.
  • The recognized moiety of the substrate is known as a type 1 histo- blood group antigen precursor disaccharide, and the action of the enzyme produces an H type 1 antigen.
  • The enzyme from the bacterium Helicobacter pylori cannot act on type 2 substrates (see EC
  • Formerly EC
PRIAM enzyme-specific profiles2.4.1.69
KEGG Ligand Database for Enzyme Nomenclature2.4.1.69
IUBMB Enzyme Nomenclature2.4.1.69
MEDLINEFind literature relating to
Q28113, FUT2_BOVIN;  O77486, FUT2_GORGO;  Q10981, FUT2_HUMAN;  
Q10982, FUT2_PIG;  O77487, FUT2_PONPY;  Q10983, FUT2_RABIT;  
Q10984, FUT2_RAT;  Q54QG0, PGFB_DICDI;  P97353, SEC1_MOUSE;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-