ENZYME entry: EC 2.4.1.69

Accepted Name
Galactoside 2-alpha-L-fucosyltransferase.
Alternative Name(s)
Alpha-(1->2)-L-fucosyltransferase.
Alpha-2-fucosyltransferase.
Alpha-2-L-fucosyltransferase.
Beta-galactoside alpha-1->2 fucosyltransferase.
Blood group H alpha-2-fucosyltransferase.
Blood-group substance H-dependent fucosyltransferase.
Galactoside 2-L-fucosyltransferase.
GDP fucose-lactose fucosyltransferase.
GDP-L-fucose:lactose fucosyltransferase.
Guanosine diphospho-L-fucose-lactose fucosyltransferase.
Guanosine diphosphofucose-beta-D-galactosyl-alpha-2-L-fucosyltransferase.
Guanosine diphosphofucose-galactoside 2-L-fucosyltransferase.
Guanosine diphosphofucose-galactosylacetylglucosaminylgalactosyl- glucosylceramide alpha-L-fucosyltransferase.
Guanosine diphosphofucose-glycoprotein 2-alpha-fucosyltransferase.
Guanosine diphosphofucose-glycoprotein 2-alpha-L-fucosyltransferase.
Guanosine diphosphofucose-lactose fucosyltransferase.
H-gene-encoded beta-galactoside alpha-1->2 fucosyltransferase.
Secretor-type beta-galactoside alpha-1->2 fucosyltransferase.
Reaction catalysed
GDP-beta-L-fucose + beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide <=> GDP + alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide
Comment(s)
  • Free lactose can act as acceptor.
  • Formerly EC 2.4.1.89.
Cross-references
BRENDA2.4.1.69
EC2PDB2.4.1.69
ExplorEnz2.4.1.69
PRIAM enzyme-specific profiles2.4.1.69
KEGG Ligand Database for Enzyme Nomenclature2.4.1.69
IUBMB Enzyme Nomenclature2.4.1.69
IntEnz2.4.1.69
MEDLINEFind literature relating to 2.4.1.69
MetaCyc2.4.1.69
UniProtKB/Swiss-Prot
Q866E1, FUT1_ALOBE;  Q866E4, FUT1_ALOCA;  Q866E6, FUT1_AOTAZ;  
Q866E7, FUT1_AOTNA;  Q9SWH5, FUT1_ARATH;  Q866C7, FUT1_ATEBE;  
Q866C5, FUT1_CALBN;  Q866D9, FUT1_CALHU;  Q9TUD4, FUT1_GORGO;  
P19526, FUT1_HUMAN;  Q866C9, FUT1_LAGLA;  Q866D6, FUT1_LEOCY;  
O09160, FUT1_MOUSE;  Q9TUD6, FUT1_PANTR;  Q9M5Q1, FUT1_PEA;  
Q29043, FUT1_PIG;  Q10979, FUT1_RABIT;  Q10980, FUT1_RAT;  
Q866D2, FUT1_SAGFU;  Q866F0, FUT1_SAIBB;  Q866F1, FUT1_SAISC;  
Q866E8, FUT1_SAPAP;  Q28113, FUT2_BOVIN;  O77486, FUT2_GORGO;  
Q10981, FUT2_HUMAN;  Q9TTC7, FUT2_HYLLA;  Q9JL27, FUT2_MOUSE;  
O77485, FUT2_PANTR;  Q10982, FUT2_PIG;  O77487, FUT2_PONPY;  
Q10983, FUT2_RABIT;  Q10984, FUT2_RAT;  Q54QG0, PGFB_DICDI;  
P97353, SEC1_MOUSE;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.-.-
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