ENZYME entry: EC 2.4.2.1

Accepted Name
Purine-nucleoside phosphorylase.
Alternative Name(s)
Inosine phosphorylase.
PNPase.
Reaction catalysed
  • Purine nucleoside + phosphate <=> purine + alpha-D-ribose 1-phosphate
  • Purine deoxynucleoside + phosphate <=> purine + 2'-deoxy-alpha-D-ribose 1-phosphate
Comment(s)
  • Specificity not completely determined.
  • Can also catalyze ribosyltransferase reactions of the type catalyzed by EC 2.4.2.5.
Cross-references
PROSITEPDOC00946 ; PDOC00954
BRENDA2.4.2.1
EC2PDB2.4.2.1
ExplorEnz2.4.2.1
PRIAM enzyme-specific profiles2.4.2.1
KEGG Ligand Database for Enzyme Nomenclature2.4.2.1
IUBMB Enzyme Nomenclature2.4.2.1
IntEnz2.4.2.1
MEDLINEFind literature relating to 2.4.2.1
MetaCyc2.4.2.1
UniProtKB/Swiss-Prot
Q6LUH1, DEOD1_PHOPR;  Q8EKK0, DEOD1_SHEON;  Q9KPM0, DEOD1_VIBCH;  
Q5E7J4, DEOD1_VIBF1;  Q87M25, DEOD1_VIBPA;  Q8DBS9, DEOD1_VIBVU;  
Q7MI41, DEOD1_VIBVY;  Q6LLA7, DEOD2_PHOPR;  Q8EHK0, DEOD2_SHEON;  
Q9KNB2, DEOD2_VIBCH;  Q5E0H4, DEOD2_VIBF1;  Q87G42, DEOD2_VIBPA;  
Q8D3Z2, DEOD2_VIBVU;  Q7MFG6, DEOD2_VIBVY;  Q8EDM4, DEOD3_SHEON;  
Q5DYV8, DEOD3_VIBF1;  A3N122, DEOD_ACTP2;  B3H1P6, DEOD_ACTP7;  
B0BPV3, DEOD_ACTPJ;  P94164, DEOD_ACTPL;  A6VM01, DEOD_ACTSZ;  
B6ER81, DEOD_ALISL;  A6TVU0, DEOD_ALKMQ;  B7GKU4, DEOD_ANOFW;  
A7Z5M8, DEOD_BACA2;  C3P552, DEOD_BACAA;  C3L9J6, DEOD_BACAC;  
A0RBS0, DEOD_BACAH;  Q81T09, DEOD_BACAN;  B7JGU6, DEOD_BACC0;  
Q73B32, DEOD_BACC1;  B7IP41, DEOD_BACC2;  C1EMV9, DEOD_BACC3;  
B7HHL7, DEOD_BACC4;  B7HKX2, DEOD_BACC7;  Q5EEL8, DEOD_BACCE;  
A7GN01, DEOD_BACCN;  B9IVI6, DEOD_BACCQ;  Q81FV5, DEOD_BACCR;  
Q63DR9, DEOD_BACCZ;  Q6HL92, DEOD_BACHK;  Q65IE9, DEOD_BACLD;  
O34925, DEOD_BACSU;  A9VLN1, DEOD_BACWK;  C0ZDZ3, DEOD_BREBN;  
B8D9W3, DEOD_BUCA5;  P57606, DEOD_BUCAI;  Q8K937, DEOD_BUCAP;  
B8D865, DEOD_BUCAT;  Q89A58, DEOD_BUCBP;  Q7NRT2, DEOD_CHRVO;  
A8ALX7, DEOD_CITK8;  A6M0X2, DEOD_CLOB8;  A0Q1A0, DEOD_CLONN;  
Q0TQJ7, DEOD_CLOP1;  Q0ST47, DEOD_CLOPS;  Q894Z3, DEOD_CLOTE;  
Q483Q8, DEOD_COLP3;  A7MIG7, DEOD_CROS8;  A5EV41, DEOD_DICNV;  
A8LJI8, DEOD_DINSH;  A7ZVS7, DEOD_ECO24;  B7UR12, DEOD_ECO27;  
B7MNJ1, DEOD_ECO45;  B7LEN0, DEOD_ECO55;  P0ABP9, DEOD_ECO57;  
B5Z4R6, DEOD_ECO5E;  B7NW64, DEOD_ECO7I;  B7N2V8, DEOD_ECO81;  
B7LXU6, DEOD_ECO8A;  C4ZT66, DEOD_ECOBW;  B1XFJ4, DEOD_ECODH;  
A8A8B3, DEOD_ECOHS;  Q0T8S9, DEOD_ECOL5;  Q8FA51, DEOD_ECOL6;  
B1IS35, DEOD_ECOLC;  P0ABP8, DEOD_ECOLI;  B7NH52, DEOD_ECOLU;  
B6I6N1, DEOD_ECOSE;  B1LEI9, DEOD_ECOSM;  C5BHJ5, DEOD_EDWI9;  
A4W6A1, DEOD_ENT38;  B2VH53, DEOD_ERWT9;  B7LNS4, DEOD_ESCF3;  
B1YJP1, DEOD_EXIS2;  C4L2Y4, DEOD_EXISA;  Q5KZM1, DEOD_GEOKA;  
P77835, DEOD_GEOSE;  C5D2F9, DEOD_GEOSW;  A4IN93, DEOD_GEOTN;  
Q7VMS8, DEOD_HAEDU;  Q4QN30, DEOD_HAEI8;  A5U9X5, DEOD_HAEIE;  
A5UH23, DEOD_HAEIG;  P44417, DEOD_HAEIN;  B8F672, DEOD_HAEPS;  
Q2SHN2, DEOD_HAHCH;  Q17YP0, DEOD_HELAH;  B6JN17, DEOD_HELP2;  
B5Z8H2, DEOD_HELPG;  Q1CS88, DEOD_HELPH;  Q9ZK38, DEOD_HELPJ;  
B2UUU1, DEOD_HELPS;  P56463, DEOD_HELPY;  Q0I1K5, DEOD_HISS1;  
B0UVM2, DEOD_HISS2;  Q28U96, DEOD_JANSC;  B5Y274, DEOD_KLEP3;  
Q59482, DEOD_KLEPN;  Q03Q52, DEOD_LACBA;  Q03CD2, DEOD_LACC3;  
B3W8N4, DEOD_LACCB;  Q9CH10, DEOD_LACLA;  O32810, DEOD_LACLM;  
Q02ZT0, DEOD_LACLS;  A5VHR2, DEOD_LACRD;  B2G592, DEOD_LACRJ;  
Q38XI0, DEOD_LACSS;  Q92AF2, DEOD_LISIN;  C1KWF5, DEOD_LISMC;  
Q71YG0, DEOD_LISMF;  B8DDP6, DEOD_LISMH;  Q8Y644, DEOD_LISMO;  
A0AJW1, DEOD_LISW6;  Q65RA4, DEOD_MANSM;  P47295, DEOD_MYCGE;  
P47724, DEOD_MYCPI;  P75053, DEOD_MYCPN;  Q1D9Z7, DEOD_MYXXD;  
Q8ENY0, DEOD_OCEIH;  Q9CLE6, DEOD_PASMU;  Q6D989, DEOD_PECAS;  
C6DKM0, DEOD_PECCP;  Q7N930, DEOD_PHOLL;  B4EWA1, DEOD_PROMH;  
Q3ICU8, DEOD_PSEHT;  A1SYK4, DEOD_PSYIN;  Q169T2, DEOD_ROSDO;  
B5F527, DEOD_SALA4;  A9MRA4, DEOD_SALAR;  Q57G38, DEOD_SALCH;  
B5FTC8, DEOD_SALDC;  B5R2J9, DEOD_SALEP;  B5R9V2, DEOD_SALG2;  
B4TH02, DEOD_SALHS;  B4T4H3, DEOD_SALNS;  Q5PK20, DEOD_SALPA;  
A9N7E3, DEOD_SALPB;  B5BAK0, DEOD_SALPK;  B4TU44, DEOD_SALSV;  
Q8Z0U2, DEOD_SALTI;  Q8ZJV7, DEOD_SALTY;  A1S477, DEOD_SHEAM;  
B8E6P7, DEOD_SHEB2;  A3D7J1, DEOD_SHEB5;  A6WRB5, DEOD_SHEB8;  
Q12QG0, DEOD_SHEDO;  Q086F7, DEOD_SHEFN;  A3QGT0, DEOD_SHELP;  
Q0HLE7, DEOD_SHESM;  Q0HXQ1, DEOD_SHESR;  B2TZR7, DEOD_SHIB3;  
Q31SV5, DEOD_SHIBS;  Q327L2, DEOD_SHIDS;  Q0SX27, DEOD_SHIF8;  
Q83P00, DEOD_SHIFL;  Q3YU09, DEOD_SHISS;  A8AXN4, DEOD_STRGC;  
Q04L76, DEOD_STRP2;  B5E3K8, DEOD_STRP4;  C1C6H0, DEOD_STRP7;  
Q1JC85, DEOD_STRPB;  Q1JM69, DEOD_STRPC;  Q1J733, DEOD_STRPF;  
A2RF09, DEOD_STRPG;  B1IB05, DEOD_STRPI;  B8ZNN8, DEOD_STRPJ;  
B2INV3, DEOD_STRPS;  A4W2M2, DEOD_STRS2;  A4VWC2, DEOD_STRSY;  
Q03KK1, DEOD_STRTD;  Q56037, DEOD_STRTR;  B9DUK0, DEOD_STRU0;  
C1CDI3, DEOD_STRZJ;  C1CJS5, DEOD_STRZP;  C1CS55, DEOD_STRZT;  
B0K889, DEOD_THEP3;  B0K6Y4, DEOD_THEPX;  Q8R973, DEOD_THETN;  
C4LAY8, DEOD_TOLAT;  O83716, DEOD_TREPA;  Q8KRT5, DEOD_XENNA;  
A1JJA0, DEOD_YERE8;  A7FMH2, DEOD_YERP3;  Q1C166, DEOD_YERPA;  
B2K3J1, DEOD_YERPB;  Q8ZIQ2, DEOD_YERPE;  A9R046, DEOD_YERPG;  
Q1CMY7, DEOD_YERPN;  A4TQJ0, DEOD_YERPP;  Q66EV7, DEOD_YERPS;  
B1JL34, DEOD_YERPY;  O66839, PNPH_AQUAE;  O28486, PNPH_ARCFU;  
P55859, PNPH_BOVIN;  B8E181, PNPH_DICTD;  Q8IMU4, PNPH_DROME;  
Q297F5, PNPH_DROPS;  P00491, PNPH_HUMAN;  B1L719, PNPH_KORCO;  
Q2RKL6, PNPH_MOOTA;  P23492, PNPH_MOUSE;  Q8U2I1, PNPH_PYRFU;  
P85973, PNPH_RAT;  Q9UTG1, PNPH_SCHPO;  Q9KYV7, PNPH_STRCO;  
P50389, PNPH_SULSO;  Q5JJB8, PNPH_THEKO;  Q05788, PNPH_YEAST;  
P46354, PUNA_BACSU;  P81989, PUNA_CELSP;  P77834, PUNA_GEOSE;  
P0A539, PUNA_MYCBO;  P46862, PUNA_MYCLE;  P9WP00, PUNA_MYCTO;  
P9WP01, PUNA_MYCTU;  P45563, XAPA_ECOLI;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.2.-
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