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ENZYME

ENZYME entry: EC 2.4.2.42

Accepted Name
UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase
Alternative Name(s)
beta-glucoside alpha-1,3-xylosyltransferase
UDP-alpha-D-xylose:beta-D-glucoside 3-alpha-D-xylosyltransferase
Reaction catalysed
3-O-(beta-D-glucosyl)-L-seryl-[EGF-like domain protein] + UDP-alpha-D-xylose <=> 3-O-[alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-seryl-[EGF-like domain protein] + H(+) + UDP
Comment(s)
  • The enzyme, found in animals and insects, is involved in the biosynthesis of the alpha-D-xylosyl-(1->3)-alpha-D-xylosyl-(1->3)- beta-D-glucosyl trisaccharide on epidermal growth factor-like (EGF- like) domains.
  • When present on Notch proteins, the trisaccharide functions as a modulator of the signaling activity of this protein.
  • Formerly EC 2.4.2.n2.
Cross-references
BRENDA2.4.2.42
EC2PDB2.4.2.42
ExplorEnz2.4.2.42
PRIAM enzyme-specific profiles2.4.2.42
KEGG Ligand Database for Enzyme Nomenclature2.4.2.42
IUBMB Enzyme Nomenclature2.4.2.42
IntEnz2.4.2.42
MEDLINEFind literature relating to 2.4.2.42
MetaCyc2.4.2.42
Rhea expert-curated reactions2.4.2.42
UniProtKB/Swiss-Prot
Q5ZKI6, GXLT1_CHICKQ5SP46, GXLT1_DANREQ4G148, GXLT1_HUMAN
Q3UHH8, GXLT1_MOUSEQ6GX83, GXLT1_RATA0PJZ3, GXLT2_HUMAN
Q810K9, GXLT2_MOUSEQ6DE37, GXLT2_XENLA

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.-.-
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