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ENZYME entry: EC 2.4.2.54

Accepted Name
Beta-ribofuranosylphenol 5'-phosphate synthase.
Alternative Name(s)
4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase.
Beta-RFA-P synthase.
Beta-RFAP synthase.
Beta-ribofuranosylaminobenzene 5'-phosphate synthase.
Reaction catalysed
5-phospho-alpha-D-ribose 1-diphosphate + 4-hydroxybenzoate <=> 4-(beta-D-ribofuranosyl)phenol 5'-phosphate + CO(2) + diphosphate
Cofactor(s)
Mn(2+) or Mg(2+).
Comment(s)
  • The enzyme is involved in biosynthesis of tetrahydromethanopterin in archaea.
  • It was initially thought to use 4-aminobenzoate as a substrate, but was later shown to utilize 4-hydroxybenzoate.
Cross-references
BRENDA2.4.2.54
EC2PDB2.4.2.54
ExplorEnz2.4.2.54
PRIAM enzyme-specific profiles2.4.2.54
KEGG Ligand Database for Enzyme Nomenclature2.4.2.54
IUBMB Enzyme Nomenclature2.4.2.54
IntEnz2.4.2.54
MEDLINEFind literature relating to 2.4.2.54
MetaCyc2.4.2.54
UniProtKB/Swiss-Prot
O28190, RFAPS_ARCFU;  Q58822, RFAPS_METJA;  O26918, RFAPS_METTH;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.-.-
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