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ENZYME entry: EC 2.4.2.57

Accepted Name
AMP phosphorylase.
Alternative Name(s)
AMPpase.
Nucleoside monophosphate phosphorylase.
Reaction catalysed
  • AMP + phosphate <=> adenine + alpha-D-ribose 1,5-bisphosphate
  • CMP + phosphate <=> cytosine + alpha-D-ribose 1,5-bisphosphate
  • UMP + phosphate <=> uracil + alpha-D-ribose 1,5-bisphosphate
Comment(s)
  • The enzyme from archaea is involved in AMP metabolism and CO(2) fixation through type III RubisCO enzymes.
  • The activity with CMP and UMP requires activation by cAMP.
Cross-references
BRENDA2.4.2.57
EC2PDB2.4.2.57
ExplorEnz2.4.2.57
PRIAM enzyme-specific profiles2.4.2.57
KEGG Ligand Database for Enzyme Nomenclature2.4.2.57
IUBMB Enzyme Nomenclature2.4.2.57
IntEnz2.4.2.57
MEDLINEFind literature relating to 2.4.2.57
MetaCyc2.4.2.57
UniProtKB/Swiss-Prot
O28928, AMPP1_ARCFU;  O28927, AMPP2_ARCFU;  A2BJU0, AMPPA_HYPBU;  
A6UUN0, AMPPA_META3;  Q8TL01, AMPPA_METAC;  Q0W5A8, AMPPA_METAR;  
A7I5N0, AMPPA_METB6;  Q466X0, AMPPA_METBF;  Q12Z64, AMPPA_METBU;  
Q2FTS5, AMPPA_METHJ;  Q58081, AMPPA_METJA;  A2SPI9, AMPPA_METLZ;  
A4FZL0, AMPPA_METM5;  A9A6M7, AMPPA_METM6;  A6VIW6, AMPPA_METM7;  
Q8Q0P9, AMPPA_METMA;  A3CSY4, AMPPA_METMJ;  Q6M0E4, AMPPA_METMP;  
A0B6C9, AMPPA_METTP;  A6URW3, AMPPA_METVS;  Q3IP82, AMPPA_NATPD;  
Q9V163, AMPPA_PYRAB;  Q8U0I2, AMPPA_PYRFU;  O59251, AMPPA_PYRHO;  
C5A1L9, AMPPA_THEGJ;  Q5JCX3, AMPPA_THEKO;  B6YWT7, AMPPA_THEON;  
A1RWC3, AMPPA_THEPD;  C6A2A0, AMPPA_THESM;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-